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CAS 526224-73-7

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Found 2 products.
  • Huwentoxin-IV
    Targetmol
    + Info

    Huwentoxin-IV

    CAS:
    Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.
    Formula:C174H278N52O51S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4106.79

    Ref: TM-TP2016

  • Huwentoxin IV
    Biosynth
    + Info

    Huwentoxin IV

    CAS:
    <p>Huwentoxin IV is a potent analgesic that has been shown to have antinociceptive properties in animals. Huwentoxin IV blocks the voltage-gated sodium channel NaV1.8 and prevents the transmission of pain signals to the brain. This drug has also been shown to inhibit the activity of voltage-gated potassium channels KV1.3 and KV1.5, which are involved in neuronal excitability, suggesting that huwentoxin IV may have other therapeutic applications. Huwentoxin IV interacts with disulfide bonds and is an effective inhibitor of voltage-gated sodium channels, but not voltage-gated potassium channels, at low concentrations (10 μM).</p>
    Formula:C174H278N52O51S6
    Purity:Min. 95%
    Molecular weight:4,107 g/mol

    Ref: 3D-BWA22473

    1mg
    3,178.00€