CAS 52628-64-5

Prednisolone 17-acetate

Description:

Prednisolone 17-acetate is a synthetic glucocorticoid and a derivative of prednisolone, primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to modulate various physiological processes, including the immune response and inflammation. The compound features a steroid backbone, which is typical of corticosteroids, and includes an acetate group at the 17-position, enhancing its lipophilicity and bioavailability. Prednisolone 17-acetate is often administered via injection and is utilized in the treatment of conditions such as allergies, autoimmune disorders, and certain types of cancer. Its mechanism of action involves binding to glucocorticoid receptors, leading to the regulation of gene expression and subsequent effects on cellular activity. The substance is known for its potential side effects, which can include weight gain, mood changes, and increased susceptibility to infections, particularly with prolonged use. As with all corticosteroids, careful monitoring and dosage adjustments are essential to minimize adverse effects while maximizing therapeutic benefits.

Formula: C₂₃H₃₀O₆

InChI: InChI=1S/C23H30O6/c1-13(25)29-23(19(28)12-24)9-7-17-16-5-4-14-10-15(26)6-8-21(14,2)20(16)18(27)11-22(17,23)3/h6,8,10,16-18,20,24,27H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

InChI key: InChIKey=YCEQGEMYOUCHON-JZYPGELDSA-N

SMILES: C(CO)(=O)[C@]1(OC(C)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]

Synonyms:

• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-, 17-acetate
• Prednisolone 17-acetate
• Prednisolone 17α-acetate
• (11β)-17-(Acetyloxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-11,21-dihydroxy-, (11β)-
• [Synonyms]

Prednisolone 17-Acetate

Controlled Product

CAS: 52628-64-5

Formula: C₂₃H₃₀O₆

Color and Shape: Neat

Molecular weight: 402.48

Ref: 86-MM0194.04

Prednisolone 17-Acetate

Controlled Product

CAS: 52628-64-5

Applications Prednisolone 17-Acetate is an intermediate in the preparation of anti-inflammatory drugs.
References Yoon, Kyoung-Jin, et al.: Steroids, 60(7), 445-51 (1995);Uszycka-Horawa, Teresa, et al.: Pol., PL 161012 B1 19930531 (1993)

Formula: C₂₃H₃₀O₆

Color and Shape: Neat

Molecular weight: 402.48

Ref: TR-P703835

Prednisolone 17-Acetate

CAS: 52628-64-5

Formula: C₂₃H₃₀O₆

Molecular weight: 402.49

Ref: ST-EA-CP-P20057