CymitQuimica logo

CAS 52665-74-4

:

Manumycin

Description:
Manumycin is a natural product with notable antibiotic and antitumor properties, primarily derived from the fermentation of certain Streptomyces species. It is classified as a polyketide and exhibits a complex structure characterized by a fused bicyclic system. Manumycin is known for its ability to inhibit the enzyme farnesyltransferase, which plays a crucial role in the post-translational modification of proteins involved in cell signaling pathways, particularly those related to cancer progression. This inhibition can lead to the disruption of malignant cell growth and proliferation. Additionally, Manumycin has shown activity against various bacterial strains, making it a subject of interest in the development of new antimicrobial agents. Its solubility properties and stability under different conditions can vary, influencing its bioavailability and therapeutic potential. Research continues to explore its mechanisms of action and potential applications in both oncology and infectious disease treatment. Overall, Manumycin represents a significant compound in the field of medicinal chemistry, with ongoing studies aimed at harnessing its biological activity for therapeutic use.
Formula:C31H38N2O7
InChI:InChI=1S/C31H38N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,28-29,34,39H,5-6,11,13-14H2,1-4H3,(H,32,38)(H,33,36)/b8-7+,12-9+,15-10+,20-16+,21-17+/t19-,28-,29-,31+/m1/s1
InChI key:InChIKey=TWWQHCKLTXDWBD-MVTGTTCWSA-N
SMILES:C(=C/C=C/C=C/C(NC=1C(=O)CCC1O)=O)\[C@@]2(O)[C@]3([C@](O3)(C(=O)C(NC(/C(=C/C(=C/[C@@H](CCCC)C)/C)/C)=O)=C2)[H])[H]
Synonyms:
  • (-)-Manumycin A
  • (2E,4E)-N-(5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2,4,6-trimethyldeca-2,4-dienamide
  • (2E,4E,6R)-N-[(1S,5S,6R)-5-Hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-2,4-decadienamide
  • (2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyldeca-2,4-dienamide
  • 2,4-Decadienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-, (2E,4E,6R)-
  • 2,4-Decadienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-, (2E,4E,6R)-
  • 7-Oxabicyclo[4.1.0]heptane, 2,4-decadienamide deriv.
  • Manumycin
  • Manumycin A, Streptomyces parvulus
  • NSC 622141
  • Ucf 1C
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.
  • Manumycin A
    Targetmol
    + Info

    Manumycin A

    CAS:
    Manumycin A is an antibiotic with anticancer activity and is a TrxR-1 inhibitor.
    Formula:C31H38N2O7
    Purity:98%
    Color and Shape:Yellow Powder
    Molecular weight:550.64

    Ref: TM-T16011

  • Manumycin A, Streptomyces parvulus
    Fluorochem
    + Info

    Manumycin A, Streptomyces parvulus

    CAS:
    Formula:C31H38N2O7
    Purity:>96%
    Color and Shape:Solid
    Molecular weight:550.652

    Ref: 10-M02091

    5mg
    1,222.00€
  • Manumycin A
    Glentham
    + Info

    Manumycin A

    CAS:
    Formula:C31H38N2O7
    Purity:≥ 98.0%
    Color and Shape:Yellow or orange-brown powder
    Molecular weight:550.64

    Ref: 7W-GL8712

    1mg
    200.00€
    5mg
    697.00€
    10mg
    1,021.00€
  • Manumycin A
    TRC
    + Info

    Manumycin A

    Controlled Product
    CAS:
    Formula:C31H38N2O7
    Color and Shape:Neat
    Molecular weight:550.64

    Ref: TR-M186000

    500µg
    346.00€
    2500µg
    1,422.00€