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CAS 52691-62-0

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1-O-Hexadecyl-sn-glycero-3-phosphocholine

Description:
1-O-Hexadecyl-sn-glycero-3-phosphocholine, commonly referred to as DHPC, is a synthetic phospholipid that plays a significant role in membrane biology and biochemistry. It features a long-chain fatty acid (hexadecyl) attached to the glycerol backbone, which contributes to its amphiphilic nature, allowing it to interact with both hydrophilic and hydrophobic environments. The presence of a phosphocholine head group enhances its solubility in aqueous solutions and facilitates interactions with biological membranes. DHPC is often utilized in the formation of liposomes and lipid bilayers, serving as a model for studying membrane dynamics and properties. Its structural characteristics enable it to stabilize membrane structures and influence membrane fluidity. Additionally, DHPC is used in various applications, including drug delivery systems and as a component in biochemical assays. Its unique properties make it a valuable tool in both research and therapeutic contexts, particularly in the study of cell membrane interactions and lipid-based formulations.
Formula:C24H52NO6P
InChI:InChI=1/C24H52NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-29-22-24(26)23-31-32(27,28)30-21-19-25(2,3)4/h24,26H,5-23H2,1-4H3/t24-/m1/s1
InChI key:InChIKey=VLBPIWYTPAXCFJ-XMMPIXPASA-N
SMILES:O(C[C@@H](COCCCCCCCCCCCCCCCC)O)P(OCC[N+](C)(C)C)(=O)[O-]
Synonyms:
  • (R)-3-(Hexadecyloxy)-2-hydroxypropyl (2-(trimethylammonio)ethyl) phosphate
  • 1-Hexadecyl-2-lyso-sn-glycero-3-phosphocholine
  • 1-O-Hexadecyl-2-lyso-sn-glycero-3-phosphocholine
  • 1-O-Hexadecyl-sn-glycero-3-phosphatidylcholine
  • 1-O-Hexadecyl-sn-glycero-3-phosphocholine
  • 1-O-Hexadecyl-sn-glyceryl-3-phosphorylcholine
  • 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-
  • 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, (R)-
  • 58: PN: WO2017201317 SEQID: 131 claimed RNA
  • Lpc O-16:0
  • See more synonyms
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