CAS 52727-57-8

Methyl 2-amino-5-bromobenzoate

Description:

Methyl 2-amino-5-bromobenzoate, with the CAS number 52727-57-8, is an organic compound that belongs to the class of benzoate esters. It features a methyl ester functional group attached to a benzoic acid derivative, which is further substituted with an amino group and a bromine atom. This compound typically appears as a crystalline solid and is characterized by its moderate solubility in organic solvents, while being less soluble in water due to its hydrophobic aromatic structure. The presence of the amino group imparts basic properties, allowing it to participate in various chemical reactions, such as nucleophilic substitutions. The bromine atom serves as a useful handle for further functionalization, making it a valuable intermediate in organic synthesis. Methyl 2-amino-5-bromobenzoate can be utilized in the development of pharmaceuticals, agrochemicals, and other fine chemicals, owing to its reactivity and the potential for further derivatization. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₈H₈BrNO₂

InChI: InChI=1S/C8H8BrNO2/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4H,10H2,1H3

InChI key: InChIKey=QVNYNHCNNGKULA-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C(N)C=CC(Br)=C1

Synonyms:

• 2-Amino-5-bromobenzoic acid methyl ester
• 5-Bromo anthranilate methyl
• 5-Bromo-2-aminobenzoic acid methyl ester
• 5-Bromoanthranilic acid methyl ester
• Anthranilic acid, 5-bromo-, methyl ester
• Benzoic acid, 2-amino-5-bromo-, methyl ester
• Methyl 5-bromo-2-aminobenzoate
• Methyl 5-bromoanthranilate
• Methyl 2-amino-5-bromobenzoate

Methyl 2-Amino-5-bromobenzoate

CAS: 52727-57-8

Formula: C₈H₈BrNO₂

Purity: >99.0%(GC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 230.06

Ref: 3B-B1988

Methyl 2-amino-5-bromobenzoate, 98%

CAS: 52727-57-8

Methyl 2-amino-5-bromobenzoate acts as a potential PqsD inhibitor against pseudomonas aeruginosa infections. It is also used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors. It is involved in plant growth-regulator activity. This Thermo Scientific Chemicals brand product was

Formula: C₈H₈BrNO₂

Purity: 98%

Color and Shape: Pale cream to cream to pale gray or pale brown, Crystals or powder or crystalline powder

Molecular weight: 230.06

Ref: 02-A16666

Methyl 2-amino-5-bromobenzoate

CAS: 52727-57-8

Formula: C₈H₈BrNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 230.0586

Ref: IN-DA00DDRZ

Methyl 2-amino-5-bromobenzoate

CAS: 52727-57-8

Methyl 2-amino-5-bromobenzoate

Formula: C₈H₈BrNO₂

Purity: 98%

Color and Shape: grey to light beige solid

Molecular weight: 230.06g/mol

Ref: 54-OR4689

Methyl 2-amino-5-bromobenzoate

CAS: 52727-57-8

Methyl 2-amino-5-bromobenzoate

Purity: ≥98%

Molecular weight: 230.06g/mol

Ref: 54-BUP19830

2-Amino-5-bromobenzoic acid methyl ester

CAS: 52727-57-8

2-Amino-5-bromobenzoic acid methyl ester is a small molecule with antiviral potency. It has a dipole moment and can form hydrogen bonds. 2-Amino-5-bromobenzoic acid methyl ester inhibits the PDE5 enzyme, which is an enzyme that breaks down cGMP. This inhibition of PDE5 leads to the increase in cGMP, which causes blood vessels to relax and widen. As a result, 2-amino-5-bromobenzoic acid methyl ester has been shown to decrease high blood pressure and improve heart function.

Formula: C₈H₈BrNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 230.06 g/mol

Ref: 3D-FA70737

Methyl 2-amino-5-bromobenzoate

CAS: 52727-57-8

Formula: C₈H₈BrNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 230.061

Ref: 10-F092776

Methyl 2-Amino-5-bromobenzoate

Controlled Product

CAS: 52727-57-8

Applications Methyl 2-Amino-5-bromobenzoate is used as a potential PqsD inhibitor against pseudomonas aeruginosa infections.
References Weidel, E. et al.: J. Med. Chem., 56, 6146 (2013);

Formula: C₈H₈BrNO₂

Color and Shape: Neat

Molecular weight: 230.06

Ref: TR-M285715

Methyl 2-amino-5-bromobenzoate

CAS: 52727-57-8

Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is an HCV NS5b RNA polymerase inhibitor with antimicrobial activity.

Formula: C₈H₈BrNO₂

Purity: 98.05%

Color and Shape: Solid

Molecular weight: 230.06

Ref: TM-T78226