CAS 528-43-8

Magnolol

Description:

Magnolol is a natural compound primarily derived from the bark of the Magnolia tree, particularly from species such as Magnolia officinalis. It is classified as a biphenolic compound, characterized by its two aromatic rings connected by a carbon chain. Magnolol exhibits a range of biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties, making it of interest in pharmacological research. The substance is typically a white to pale yellow crystalline solid with a melting point that varies depending on purity and specific conditions. It is soluble in organic solvents like ethanol and methanol but has limited solubility in water. Magnolol has been studied for its potential therapeutic effects, including its role in anxiety reduction and its ability to enhance cognitive function. Additionally, it is being explored for its potential applications in food preservation and cosmetics due to its antimicrobial properties. Overall, magnolol represents a significant compound in both traditional medicine and modern scientific research.

Formula: C₁₈H₁₈O₂

InChI: InChI=1/C18H18O2/c1-3-5-13-7-9-17(19)15(11-13)16-12-14(6-4-2)8-10-18(16)20/h3-4,7-12,19-20H,1-2,5-6H2

InChI key: InChIKey=VVOAZFWZEDHOOU-UHFFFAOYSA-N

SMILES: OC=1C(=CC(CC=C)=CC1)C2=CC(CC=C)=CC=C2O

Synonyms:

• 2,2′-Bichavicol
• 2,2′-Biphenyldiol, 5,5′-diallyl-
• 2-(2-Hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphenol
• 5,5'-Di(Prop-2-En-1-Yl)Biphenyl-2,2'-Diol
• 5,5′-Di-2-propen-1-yl[1,1′-biphenyl]-2,2′-diol
• 5,5′-Diallyl-2,2′-biphenyldiol
• Magnolia Extract
• NSC 293099
• [1,1′-Biphenyl]-2,2′-diol, 5,5′-di-2-propen-1-yl-
• [1,1′-Biphenyl]-2,2′-diol, 5,5′-di-2-propenyl-
• Honokiol std.
• MAGNOLOL
• Magnolol std.
• 5',5-di-2-propenyl-(1,1'-Biphenyl)-2,2'-diol
• 5,5'-DIALLYL-BIPHENYL-2,2'-DIOL
• MAGNOLOL(SH)
• 1’-Biphenyl)-2,2’-diol,5’,5-di-2-propenyl-(1
• Magnolia officinalis Rehd.et Wils
• MAGNOLIABARKEXTRACT
• 5,5'-DIALLYL-2,2'-DIHYDROXYBIPHENYL
• MAGNOLOL 98.0% BY HPLC

Magnolol

CAS: 528-43-8

Formula: C₁₈H₁₈O₂

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 266.34

Ref: 3B-D3971

Magnolol

CAS: 528-43-8

Magnolol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₈H₁₈O₂

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 266.34

Ref: 11-4998S

MAGNOLOL CRS

CAS: 528-43-8

MAGNOLOL CRS

Formula: C₁₈H₁₈O₂

Molecular weight: 266.3343

Ref: 41-Y0001289

Magnolol

CAS: 528-43-8

Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.

Formula: C₁₈H₁₈O₂

Purity: 99.49%

Color and Shape: A Bioactive Compound Found In The Bark Of The Houpu Magnolia

Molecular weight: 266.33

Ref: TM-T3000

Magnolol

CAS: 528-43-8

Formula: C₁₈H₁₈O₂

Molecular weight: 266.34

Ref: 4Z-M-252001

Magnolol

CAS: 528-43-8

Magnolol

Purity: ≥98%

Molecular weight: 266.33g/mol

Ref: 54-BUP11936

Magnolol

CAS: 528-43-8

Formula: C₁₈H₁₈O₂

Purity: ≥ 97.0% (dried basis)

Color and Shape: White to off-white powder or crystals

Molecular weight: 266.3

Ref: 7W-GA6326

Magnolol

CAS: 528-43-8

Magnolol is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 μM and 17.7 μM, respectively. Magnolol has antifungal, antibacterial, anti-oxidative, antidepressant-like, anti- tumor, and neuroprotective effects, it also prevents skin photoaging in UVB-irradiated hairless mice. Magnolol has a wide spectrum of targets including TNF-α, NF-KB, GSK3β.

Formula: C₁₈H₁₈O₂

Purity: 95%~99%

Molecular weight: 266.34

Ref: BP-BP0916

Magnolol

CAS: 528-43-8

Polyphenol

Formula: C₁₈H₁₈O₂

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 266.34

Ref: 5G-89317

Magnolol

Controlled Product

CAS: 528-43-8

Applications Magnolol is the bioactive phytochemicals found in Magnolia officinalis (1). Magnolol has been used to treat anxiety, cough, headache and allergies (2). It also inhibits tumor necrosis factor-α-*induced ICAM-1 expression in human lung epithelial cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Amorati, R., et al.: J Org Chem. (2015) 80:10651-9.(2) Wu, C., et. al.: Inflammation (2014) 37:1957-67

Formula: C₁₈H₁₈O₂

Color and Shape: Off-White

Molecular weight: 266.33

Ref: TR-M110390

Magnolol

CAS: 528-43-8

Magnolol is a bioactive compound, which is a type of lignan extracted from the bark of the magnolia tree, primarily Magnolia officinalis. It exhibits a diverse range of pharmacological activities, primarily attributed to its anti-inflammatory and antioxidant properties. Through the modulation of various signaling pathways, including the NF-κB pathway, magnolol effectively inhibits the activation of inflammatory mediators and scavenges free radicals.

Formula: C₁₈H₁₈O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 266.33 g/mol

Ref: 3D-FM09710

5,5′-Diallyl-[1,1′-biphenyl]-2,2′-diol

CAS: 528-43-8

Formula: C₁₈H₁₈O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 266.34

Ref: 10-F079442

Magnolol

CAS: 528-43-8

Formula: C₁₈H₁₈O₂

Color and Shape: Solid

Molecular weight: 266.3343

Ref: IN-DA003549