CAS 529-28-2

2-Iodoanisole

Description:

2-Iodoanisole, also known as 2-iodo-1-methoxybenzene, is an organic compound characterized by the presence of an iodine atom and a methoxy group attached to a benzene ring. Its molecular formula is C8H9I, and it features a phenolic structure where the iodine substituent is located at the ortho position relative to the methoxy group. This compound is typically a colorless to pale yellow liquid with a characteristic aromatic odor. It is moderately soluble in organic solvents like ethanol and ether but has limited solubility in water due to its hydrophobic nature. 2-Iodoanisole is often used in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals, as well as in coupling reactions such as the Suzuki reaction. Its reactivity is influenced by the presence of the iodine atom, which can participate in nucleophilic substitution reactions. Safety precautions should be taken when handling this compound, as iodine can be hazardous, and proper storage conditions should be maintained to prevent degradation.

Formula: C₇H₇IO

InChI: InChI=1/C7H7IO/c1-9-7-5-3-2-4-6(7)8/h2-5H,1H3

InChI key: InChIKey=DVQWNQBEUKXONL-UHFFFAOYSA-N

SMILES: O(C)C1=C(I)C=CC=C1

Synonyms:

• 1-Iodo-2-Methoxy-Benzen
• 1-Iodo-2-Methoxybenzene
• 2-Iodoanisole 97%
• 2-Iodoanisole,99%
• 2-Iodoanisole97%
• 2-Iodophenyl Methyl Ether
• 2-Methoxy-1-iodobenzene
• 2-Methoxyiodobenzene
• 2-Methoxyphenyl iodide
• Anisole, o-iodo-
• Benzene, 1-iodo-2-methoxy-
• Iodanisol
• NSC 9259
• O-Iodoanisole
• o-Anisyl iodide
• o-Iodomethoxybenzene
• o-Methoxyiodobenzene
• o-Methoxyphenyl iodide
• 2-Iodoanisole
• 2-Iodo-1-methoxybenzene
• 1-Methoxy-2-iodobenzene
• 2-IODOANISOLE/1-IODO-2-METHOXYBENZENE
• 2-Iodoanisole (stabilized with Copper chip)
• 2-Iodophenyl methyl ether, 2-Methoxyiodobenzene

2-Iodoanisole, 99%

CAS: 529-28-2

2-Iodoanisole has been used in palladium/copper-catalyzed synthesis of o-(1-alkynyl)anisoles. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar produc

Formula: C₇H₇IO

Purity: 99%

Color and Shape: Clear pale yellow to yellow, Liquid

Molecular weight: 234.04

Ref: 02-A10150

1-Iodo-2-methoxybenzene

CAS: 529-28-2

Formula: C₇H₇IO

Purity: 97%

Color and Shape: Liquid

Molecular weight: 234.0343

Ref: IN-DA0033D4

2-Iodoanisole

CAS: 529-28-2

2-Iodoanisole

Purity: 98%

Color and Shape: Pale Yellow Liquid

Molecular weight: 234.03g/mol

Ref: 54-OR4678

2-Iodoanisole

CAS: 529-28-2

Formula: C₇H₇IO

Molecular weight: 234.03

Ref: 7W-GX2459

2-Iodoanisole (stabilized with Copper chip)

CAS: 529-28-2

Formula: C₇H₇IO

Purity: >98.0%(GC)

Color and Shape: White to Yellow to Green clear liquid

Molecular weight: 234.04

Ref: 3B-I0382

1-Iodo-2-methoxybenzene

CAS: 529-28-2

1-Iodo-2-methoxybenzene is a compound that has shown to have anti-cancer properties. It is an effective inhibitor of protein tyrosine kinases, which are involved in the activation of inflammatory diseases and cancer. The hydroxyl group on the benzenoid ring activates the molecule by hydrogen bonding with the protein target, thereby inhibiting its activity. 1-Iodo-2-methoxybenzene may also be used as a contrast agent for magnetic resonance imaging (MRI) due to its light emission properties.

Formula: C₇H₇IO

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 234.03 g/mol

Ref: 3D-FI54812

2-Iodoanisole

CAS: 529-28-2

Formula: C₇H₇IO

Purity: 97%

Color and Shape: Liquid

Molecular weight: 234.036

Ref: 10-F001302

2-Iodoanisole

Controlled Product

CAS: 529-28-2

Applications 2-Iodoanisole is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.
References Chu, X., et al.: J. Med. Chem., 49, 6549 (2006); Thevenin, M., et al.: Bioorg. Med. Chem., 21, 4885 (2013)

Formula: C₇H₇IO

Color and Shape: Neat

Molecular weight: 234.03

Ref: TR-I686855