CAS 52950-19-3

(S)-2-Chloromandelic acid

Description:

(S)-2-Chloromandelic acid is an organic compound characterized by its chiral nature, featuring a chiral center at the second carbon atom. It is a derivative of mandelic acid, where a chlorine atom is substituted at the 2-position of the aromatic ring. This compound typically appears as a white to off-white crystalline solid and is soluble in polar solvents such as water and alcohols. The presence of the carboxylic acid functional group contributes to its acidic properties, while the chlorine substituent can influence its reactivity and biological activity. (S)-2-Chloromandelic acid is of interest in pharmaceutical chemistry, particularly in the synthesis of various biologically active compounds. Its chirality is significant in determining its interaction with biological systems, making it a subject of study in stereochemistry and medicinal chemistry. Additionally, it may exhibit different physical and chemical properties compared to its enantiomer, which can be crucial for its application in drug development and other chemical processes.

Formula: C₈H₇ClO₃

InChI: InChI=1S/C8H7ClO3/c9-6-4-2-1-3-5(6)7(10)8(11)12/h1-4,7,10H,(H,11,12)/t7-/m0/s1

InChI key: InChIKey=RWOLDZZTBNYTMS-ZETCQYMHSA-N

SMILES: [C@H](C(O)=O)(O)C1=C(Cl)C=CC=C1

Synonyms:

• (+)-2-Chloromandelic acid
• (2S)-2-(2-Chlorophenyl)-2-hydroxyacetic acid
• (S)-(+)-2-Hydroxy-2-(2-chlorophenyl)acetic acid
• (S)-2-(2-Chlorophenyl)-2-hydroxyethanoic acid
• (S)-2-Chloromandelic Acid
• (αS)-2-Chloro-α-hydroxybenzeneacetic acid
• Benzeneacetic acid, 2-chloro-α-hydroxy-, (S)-
• Benzeneacetic acid, 2-chloro-α-hydroxy-, (αS)-
• L-(+)-2-Chloromandelic acid

2-Chloro-L-mandelic Acid

CAS: 52950-19-3

Formula: C₈H₇ClO₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 186.59

Ref: 3B-C2738

(S)-2-(2-Chlorophenyl)-2-hydroxyacetic acid

CAS: 52950-19-3

Formula: C₈H₇ClO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 186.5924

Ref: IN-DA003CGJ

(S)-(+)-2-Chloromandelic acid

CAS: 52950-19-3

(S)-(+)-2-Chloromandelic acid

Purity: 98%

Molecular weight: 186.59g/mol

Ref: 54-OR315006

(S)-(+)-2-Chloromandelic acid

CAS: 52950-19-3

Formula: C₈H₇ClO₃

Molecular weight: 186.59

Ref: 7W-GK9759

Carisbamate Impurity 2

CAS: 52950-19-3

Formula: C₈H₇ClO₃

Molecular weight: 186.59

Ref: 4Z-C-6417

(S)-2-(2-Chlorophenyl)-2-hydroxyacetic acid

CAS: 52950-19-3

Formula: C₈H₇ClO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 186.59

Ref: 10-F209997

(S)-2-Chloromandelic Acid

Controlled Product

CAS: 52950-19-3

Applications Used for chiral resolutions.
References Wang, P., et al.: Biotechnol. Bioengin., 98, 30 (2007), Mamidi, R., et al.; Drug Metab. Disposition, 35, 566 (2007), Zhang, T., et al.: J. Pharm. Biomed. Anal., 46, 882 (2008),

Formula: C₈H₇ClO₃

Color and Shape: Neat

Molecular weight: 186.59

Ref: TR-C432670