CAS 53-16-7

Estrone

Description:

Estrone is a naturally occurring estrogen steroid hormone, classified as a phenolic compound. It is primarily produced in the ovaries, adrenal glands, and peripheral tissues, playing a crucial role in the regulation of the female reproductive system and secondary sexual characteristics. Estrone is characterized by its molecular formula, which consists of carbon, hydrogen, and oxygen atoms, and it has a specific three-dimensional structure that allows it to bind to estrogen receptors in target tissues. This binding initiates various biological responses, including the regulation of the menstrual cycle and maintenance of pregnancy. Estrone is less potent than estradiol, another major estrogen, but it is significant in postmenopausal women, where it becomes the predominant form of estrogen. In addition to its physiological roles, estrone is also studied for its implications in various health conditions, including hormone replacement therapy and its potential link to certain cancers. Its CAS number, 53-16-7, uniquely identifies it in chemical databases, facilitating research and regulatory processes.

Formula: C₁₈H₂₂O₂

InChI: InChI=1/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14?,15-,16?,18+/m1/s1

InChI key: InChIKey=DNXHEGUUPJUMQT-CBZIJGRNSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CCC2=O)[H]

Synonyms:

• (8R,13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
• (8R,9S,13S,14S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one
• 1,3,5(10)-Estratrien-3-Ol-17-One
• 3-Hydroxy-1,3,5(10)-estratrien-17-one
• 3-Hydroxy-17-keto-estra-1,3,5-triene
• 3-Hydroxyestra-1,3,5(10)-Trien-17-One
• 3-Hydroxyestra-1,3,5(10)-triene-17-one
• 3-Hydroxyoestra-1,3,5(10)-trien-17-one
• 3beta-Hydroxyestra-1,3,5(10)-trien-17-one
• Aquacrine
• Crinovaryl
• Cristallovar
• Crystogen
• Destrone
• Disynformon
• Endofolliculina
• Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
• Estrol
• Estron
• Estrona
• Estrovarin
• Estrugenone
• Estrusol
• Femestrone Inj.
• Femestrone injection
• Femidyn
• Fermidyn
• Folikrin
• Folipex
• Folisan
• Follestrine
• Follestrol
• Follicular hormone
• Folliculin
• Folliculin (steroid)
• Folliculinum
• Follicunodis
• Follidrin
• Glandubolin
• Hiestrone
• Hormofollin
• Hormovarine
• Kestrone
• Ketodestrin
• Ketohydroxyestrin
• Kolpon
• Menagen
• Menformon
• Nsc 9699
• Oestrin
• Oestroform
• Oestrone
• Oestroperos
• Ovifollin
• Perlatan
• Solliculin
• Theelin
• Thelestrin
• Thelykinin
• Thynestron
• Tokokin
• Unden
• Way 164397
• Wynestron
• beta-Estrone
• Δ1,3,5(10)-Estratrien-3-ol-17-one
• Δ^1,3,5(10)-Estratrien-3-ol-17-one
• Estrone
• OESTRONE (E1)
• 1,3,5-ESTRATRIEN-3-OL-17-ONE
• 3-HYDROXY-ESTRA-1,3,5(10)-TRIEN-17-ONE
• (8R,13S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one
• E 1
• 1,3,5-Oestratrien-3-ol-17-one
• 1,3,5(10)-Oestratrien-3-ol-17-one
• 1,3,5[10]-ESTRATRIENE-3-OL-17-ONE

Estrone-d7

Controlled Product

CAS: 53-16-7

Applications Estrone-d7 is an isotope labelled metabolite of 17β-Estradiol. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.

Formula: C₁₈H₁₅D₇O₂

Color and Shape: Neat

Molecular weight: 356.323

Ref: TR-E889054

Estrone-d5

Controlled Product

CAS: 53-16-7

Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.

Formula: C₁₈H₁₇D₅O₂

Color and Shape: Neat

Molecular weight: 275.4

Ref: TR-E889053

1,3,5(10)-Estratrien-3-ol-17-one

Controlled Product

CAS: 53-16-7

1,3,5(10)-Estratrien-3-ol-17-one is a steroid hormone, commonly referred to as Estrone, which is an endogenous estrogen. It is primarily synthesized from cholesterol through a series of biochemical transformations. The main sources of Estrone include the ovaries, adipose tissue, and certain pathways in the liver, making it prevalent in the human body, particularly in females.

Formula: C₁₈H₂₂O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 270.37 g/mol

Ref: 3D-FE22839

DL-Estrone-(13,14,15,16,17,18-13C6)

Controlled Product

CAS: 53-16-7

Formula: C₁₂C₆H₂₂O₂

Color and Shape: Neat

Molecular weight: 276.32

Ref: TR-E889049

Estrone

CAS: 53-16-7

Color and Shape: Neat

Ref: 61-FOR0282.00

Estrone

Controlled Product

CAS: 53-16-7

Formula: C₁₈H₂₂O₂

Color and Shape: Neat

Molecular weight: 270.37

Ref: 86-MM0282.00