CAS 53-21-4

(-)-Cocaine hydrochloride

Description:

(-)-Cocaine hydrochloride is the hydrochloride salt form of cocaine, a potent alkaloid derived from the leaves of the coca plant, Erythroxylum coca. It is a white crystalline powder that is soluble in water and has a bitter taste. As a local anesthetic, it acts by blocking sodium channels, thereby inhibiting nerve impulse transmission. This property makes it useful in certain medical applications, particularly in dentistry and otolaryngology. The substance exhibits stimulant effects on the central nervous system, leading to increased energy, alertness, and euphoria, but it also has a high potential for abuse and addiction. Its pharmacological effects are primarily mediated through the inhibition of dopamine reuptake in the brain. Due to its potential for misuse, (-)-cocaine hydrochloride is classified as a controlled substance in many countries. Safety and handling precautions are essential when dealing with this compound, as it can pose significant health risks, including cardiovascular issues and neurological effects.

Formula: C₁₇H₂₁NO₄·ClH

InChI: InChI=1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1

InChI key: InChIKey=PIQVDUKEQYOJNR-VZXSFKIWSA-N

SMILES: C(OC)(=O)[C@@H]1[C@@]2(N(C)[C@](C[C@@H]1OC(=O)C3=CC=CC=C3)(CC2)[H])[H].Cl

Synonyms:

• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester), hydrochloride
• 1αH,5αH-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester), hydrochloride
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride (1:1), (1R,2R,3S,5S)-
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride, (1R,2R,3S,5S)-
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride, [1R-(exo,exo)]-
• Cocaina, Clorhidrato
• Cocaine HCl
• Cocaine Hydrochloride
• Cocaine chloride
• Cocaine muriate
• Cocaine, Chlorhydrate
• Cocainhydrochlorid
• Mcv 4526
• Nih 8211
• Nsc 25263
• Sal de Merck
• l-Cocaine hydrochloride
• methyl (1R,2R,3S,5R)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride (1:1)
• methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride (1:1)

Cocaine Hydrochloride

Controlled Product

CAS: 53-21-4

Color and Shape: Neat

Ref: 61-FOR1345.00

Cocaine.HCl, 1mg/ml in Methanol (as free base)

Controlled Product

CAS: 53-21-4

Color and Shape: Single Solution

Ref: LP-COC-156-HC-1LM

Cocaine.HCl

Controlled Product

CAS: 53-21-4

Color and Shape: Neat

Ref: LP-COC-156-HC-10

Cocaine Hydrochloride

Controlled Product

CAS: 53-21-4

Color and Shape: Neat

Ref: 86-MM1345.00

Cocaine Hydrochloride

Controlled Product

CAS: 53-21-4

Applications Inhibits the dopamine, norepinephrine, and serotonin transporters. Unlike amphetamines, it has no effect on catecholamine release. Controlled substance. Anesthetic (local).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blakely, R.D., et al.: Curr. Opin. Neurobiol., 10, 328 (2000), Cowell, R. M., et al.: Eur. J. Pharmacol., 389, 59 (2000), Fleckenstein, A.E., Eur. J. Pharmacol., 406, 1 (2000), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),

Formula: C₁₇H₂₁NO₄·ClH

Color and Shape: White To Off-White

Molecular weight: 339.81

Ref: TR-C633500

Cocaine hydrochloride

Controlled Product

CAS: 53-21-4

Cocaine hydrochloride

Formula: C₁₇H₂₁NO₄HCl

Purity: 99.4%

Color and Shape: White. To. Off-White

Molecular weight: 339.12374

Ref: 47-715

Cocaine Hydrochloride (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 53-21-4

Formula: C₁₇H₂₁NO₄·ClH

Color and Shape: Single Solution

Molecular weight: 339.81

Ref: TR-KIT3800

Cocaine Hydrochloride (1 mg/ml in Methanol)

Controlled Product

CAS: 53-21-4

Formula: C₁₇H₂₁NO₄·ClH

Color and Shape: Single Solution

Molecular weight: 339.81

Ref: TR-KIT2485

Cocaine Hydrochloride CII

Controlled Product

CAS: 53-21-4

Cocaine, ecgonine; salts, esters and other derivatives thereof

Formula: C₁₇H₂₁NO₄·ClH

Color and Shape: Colorless White Crystalline Powder

Molecular weight: 339.12374

Ref: 45-1143008

Cocaine hydrochloride

Controlled Product

CAS: 53-21-4

Cocaine hydrochloride is a natural compound obtained from the leaves of the coca plant. Cocaine hydrochloride is a stimulant drug that affects the central nervous system and increases blood pressure, heart rate, and body temperature. Cocaine hydrochloride also has been found to have bowel disease-related physiological effects in humans. Cocaine hydrochloride's mechanism of action is not fully understood but it may be related to its ability to bind to the dopamine transporter protein in nerve cells and inhibit dopamine reuptake. Cocaine hydrochloride can also act as an antimicrobial agent by inhibiting bacterial growth by blocking ribosomal RNA synthesis.

Formula: C₁₇H₂₂ClNO₄

Purity: Min. 98%

Color and Shape: Powder

Molecular weight: 339.81 g/mol

Ref: 3D-FC20529