CAS 53-21-4: (-)-Cocaine hydrochloride
Description:(-)-Cocaine hydrochloride is the hydrochloride salt form of cocaine, a potent alkaloid derived from the leaves of the coca plant, Erythroxylum coca. It is a white crystalline powder that is soluble in water and has a bitter taste. As a local anesthetic, it acts by blocking sodium channels, thereby inhibiting nerve impulse transmission. This property makes it useful in certain medical applications, particularly in dentistry and otolaryngology. The substance exhibits stimulant effects on the central nervous system, leading to increased energy, alertness, and euphoria, but it also has a high potential for abuse and addiction. Its pharmacological effects are primarily mediated through the inhibition of dopamine reuptake in the brain. Due to its potential for misuse, (-)-cocaine hydrochloride is classified as a controlled substance in many countries. Safety and handling precautions are essential when dealing with this compound, as it can pose significant health risks, including cardiovascular issues and neurological effects.
Formula:C17H21NO4·ClH
InChI:InChI=1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1
InChI key:InChIKey=PIQVDUKEQYOJNR-VZXSFKIWSA-N
SMILES:Cl.O=C(OC1CC2N(C)C(CC2)C1C(=O)OC)C=3C=CC=CC3
- Synonyms:
- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester), hydrochloride
- 1αH,5αH-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester), hydrochloride
- 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride (1:1), (1R,2R,3S,5S)-
- 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride, (1R,2R,3S,5S)-
- 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride, [1R-(exo,exo)]-
- Cocaina, Clorhidrato
- Cocaine HCl
- Cocaine Hydrochloride
- Cocaine chloride
- Cocaine muriate
- See more synonyms
- Cocaine, Chlorhydrate
- Cocainhydrochlorid
- Mcv 4526
- Nih 8211
- Nsc 25263
- Sal de Merck
- l-Cocaine hydrochloride
- methyl (1R,2R,3S,5R)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride (1:1)
- methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride (1:1)
- methyl (1S,2S,3R,5R)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride (1:1)
