CAS 53-85-0
:5,6-Dichloro-1-(β-D-ribofuranosyl)benzimidazole
Description:
5,6-Dichloro-1-(β-D-ribofuranosyl)benzimidazole is a chemical compound characterized by its structure, which includes a benzimidazole core substituted with two chlorine atoms at the 5 and 6 positions and a β-D-ribofuranosyl group at the 1 position. This compound is known for its role as an antiviral agent, particularly in the context of inhibiting viral replication. It exhibits properties typical of benzimidazole derivatives, such as potential interactions with nucleic acids and enzymes. The presence of the ribofuranosyl moiety enhances its biological activity by facilitating incorporation into nucleic acid structures. Its molecular weight and solubility characteristics can vary based on the solvent used, but it is generally soluble in polar solvents. The compound's CAS number, 53-85-0, is a unique identifier that aids in its classification and retrieval in chemical databases. Overall, 5,6-Dichloro-1-(β-D-ribofuranosyl)benzimidazole is significant in medicinal chemistry and virology research.
Formula:C12H12Cl2N2O4
InChI:InChI=1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1
InChI key:InChIKey=XHSQDZXAVJRBMX-DDHJBXDOSA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=CC(Cl)=C(Cl)C3)O[C@H](CO)[C@H]1O
Synonyms:- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5,6-dichlorobenzimidazole
- 1H-Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 5,6-Dichloro-1-(β-<span class="text-smallcaps">D</span>-ribofuranosyl)benzimidazole
- 5,6-Dichloro-1-b-D-ribofuranosylbenzimidazole
- 5,6-Dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
- 5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside
- 5,6-Dichlorobenzimidazole 1-β-<span class="text-smallcaps">D</span>-ribofuranoside
- 5,6-Dichlororibofuranosylbenzimidazole
- 5,6-dichloro-1-(beta-D-ribofuranosyl)-1H-benzimidazole
- 5,6-dichloro-1-[(2xi)-beta-D-threo-pentofuranosyl]-1H-benzimidazole
- 5,6-dichloro-1-pentofuranosyl-1H-benzimidazole
- Benzimidazole, 5,6-dichloro-1-<span class="text-smallcaps">D</span>-ribofuranosyl-
- Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- NSC 401575
- Nqz-002
- 5,6-Dichloro-1-β-D-ribofuranosyl-1H-benzimidazole
- 5,6-Dichloro-1-(β-D-ribofuranosyl)benzimidazole
- 1H-Benzimidazole, 5,6-dichloro-1-β-D-ribofuranosyl-
- Benzimidazole, 5,6-dichloro-1-D-ribofuranosyl-
- See more synonyms
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Found 11 products.
5,6-Dichlorobenzimidazole 1-β-D-Ribofuranoside
CAS:Formula:C12H12Cl2N2O4Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:319.145,6-Dichlorobenzimidazole riboside, 98%
CAS:<p>Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases. This The</p>Formula:C12H12Cl2N2O4Purity:98%Color and Shape:White to pale cream, PowderMolecular weight:319.141H-Benzimidazole, 5,6-dichloro-1-b-D-ribofuranosyl-
CAS:Formula:C12H12Cl2N2O4Purity:98%Color and Shape:SolidMolecular weight:319.14075,6-Dichlorobenzimidazole 1-β-D-ribofuranoside
CAS:5,6-Dichlorobenzimidazole 1-β-D-ribofuranosideMolecular weight:319.14g/molDRB
CAS:<p>DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)</p>Formula:C12H12Cl2N2O4Purity:99.46% - 99.83%Color and Shape:White To Off-White Crystalline SolidMolecular weight:319.145,6-Dichloropurine-1-β-D-ribofuanosyl-H-benzimidazole
CAS:Controlled Product<p>Applications An inhibitor of RNA synthesis (causes premature termination of transcription).<br>References Braedlye, J. and Sporns, O.: Brain Res., 815, 140 (1999), Ljungman, M., et al.: Oncogene, 18, 583 (1999), Roele, R.H., et al.: Oncogene, 18, 5765 (1999)<br></p>Formula:C12H12Cl2N2O4Color and Shape:NeatMolecular weight:319.145,6-Dichlorobenzimidazole-1-b-D-ribofuranoside
CAS:<p>5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside is a chemical compound that has been shown to be neurotoxic in vitro. It has significant cytotoxicity against human leukemia cells (HL60) and induces neuronal death. This drug also inhibits the production of neurotrophic factors, which are vital for the normal development of neurons. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside inhibits transcriptional regulation of genes that encode for receptors and enzymes. The compound is chemically stable and does not degrade easily by hydrolysis or oxidation. It can bind to polymerase chain reaction (PCR) primers and inhibit DNA synthesis. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside also affects cell nuclei by inhibiting DNA synthesis and enzyme activities.</p>Formula:C12H12Cl2N2O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:319.15 g/mol(2R,3R,4S,5R)-2-(5,6-Dichloro-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:Purity:98%Molecular weight:319.1400146
![(2R,3R,4S,5R)-2-(5,6-Dichloro-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF869536.jpg&w=3840&q=75)
