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CAS 53016-31-2

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Norelgestromin

Description:
Norelgestromin is a synthetic progestin, primarily used in hormonal contraceptives. It is a derivative of the natural hormone progesterone and is characterized by its ability to mimic the effects of progesterone in the body. Norelgestromin is known for its high oral bioavailability and is often administered transdermally via patches, allowing for sustained release into the bloodstream. The substance has a molecular formula that reflects its complex structure, which includes multiple rings and functional groups that contribute to its hormonal activity. Norelgestromin functions by inhibiting ovulation, altering the endometrial lining, and thickening cervical mucus, thereby preventing pregnancy. Its pharmacokinetics involve metabolism primarily in the liver, and it is excreted through urine. The compound is generally well-tolerated, but like all medications, it may have side effects and contraindications that should be considered. Overall, Norelgestromin plays a significant role in reproductive health, particularly in contraceptive formulations.
Formula:C21H29NO2
InChI:InChI=1S/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1
InChI key:InChIKey=ISHXLNHNDMZNMC-XUDSTZEESA-N
SMILES:C(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=NO)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]
Synonyms:
  • (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Oxime
  • (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-(hydroxyimino)-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)
  • 17-Deacetylnorgestimate
  • 17-Deacylnorgestimate
  • 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, oxime, (17α)-
  • 18-Methylnorethindrone oxime
  • <span class="text-smallcaps">D</span>-Norgestrel 3-oxime
  • Brn 4202099
  • D-Norgestrel 3-oxime
  • Levonorgestrel 3-oxime
  • See more synonyms
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