CAS 53023-18-0

(9R,10R)-9-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-10-yl 3-methylbut-2-enoate

Description:

The chemical substance known as "(9R,10R)-9-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-10-yl 3-methylbut-2-enoate," with the CAS number 53023-18-0, is a complex organic compound characterized by its unique structural features. It belongs to the class of pyranochromenes, which are known for their diverse biological activities and potential applications in medicinal chemistry. The presence of an acetyloxy group suggests that it may exhibit ester-like properties, influencing its reactivity and solubility. The compound's structure includes multiple chiral centers, indicating that it may exist in different stereoisomeric forms, which can significantly affect its biological activity and pharmacokinetics. Additionally, the presence of a 3-methylbut-2-enoate moiety indicates potential for further chemical reactivity, such as undergoing hydrolysis or participating in polymerization reactions. Overall, this compound's intricate structure and functional groups contribute to its potential utility in various chemical and pharmaceutical applications.

Formula: C₂₁H₂₂O₇

InChI: InChI=1/C21H22O7/c1-11(2)10-16(24)27-19-17-14(28-21(4,5)20(19)25-12(3)22)8-6-13-7-9-15(23)26-18(13)17/h6-10,19-20H,1-5H3/t19-,20-/m1/s1

InChI key: InChIKey=VPDWBGHNQKUFNN-WOJBJXKFSA-N

SMILES: O(C(C=C(C)C)=O)[C@@H]1C=2C3=C(C=CC2OC(C)(C)[C@@H]1OC(C)=O)C=CC(=O)O3

Synonyms:

• 2-Butenoic acid, 3-methyl-, 9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b′]dipyran-10-yl ester, (9R-cis)-
• 3′(R),4′(R)-3′-Acetoxy-4′-senecioyloxy-3′,4′-dihydroseselin
• 2H,8H-Benzo[1,2-b:3,4-b′]dipyran, 2-butenoic acid deriv.
• 2-Butenoic acid, 3-methyl-, (9R,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b′]dipyran-10-yl ester
• Isosamidin
• 3-Methyl-2-butenoic acid 9α-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10α-yl ester

(-)-Isosamidin

CAS: 53023-18-0

Formula: C₂₁H₂₂O₇

Color and Shape: Off White Powder

Molecular weight: 386.4

Ref: TR-S110505

(-)-Isosamidin

CAS: 53023-18-0

Isosamidin is a coumarin derivative that has been shown to be effective in the treatment of bladder diseases. In clinical studies, isosamidin has been shown to reduce the symptoms of bladder disease, as well as increase bladder capacity and decrease the frequency of nighttime urination. Isosamidin inhibits the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), which are molecules that can cause tissue damage or cell death. Isosamidin also reduces inflammation by inhibiting the production of arachidonic acid from phospholipids in the cell membrane and inhibiting cyclooxygenase enzymes.

Formula: C₂₁H₂₂O₇

Purity: Min. 95%

Molecular weight: 386.4 g/mol

Ref: 3D-DCA02318