CAS 531-85-1

[1,1′-Biphenyl]-4,4′-diamine hydrochloride (1:2)

Description:

[1,1′-Biphenyl]-4,4′-diamine hydrochloride, also known as benzidine hydrochloride, is an organic compound characterized by its biphenyl structure with amino groups at the para positions. It appears as a white to light yellow crystalline solid and is soluble in water and alcohol, which facilitates its use in various chemical applications. This compound is primarily utilized in the synthesis of dyes, particularly azo dyes, due to its ability to undergo diazotization and coupling reactions. However, it is important to note that benzidine and its derivatives are associated with significant health risks, including carcinogenicity, leading to strict regulations regarding their use and handling. The hydrochloride form enhances its stability and solubility, making it easier to work with in laboratory settings. Safety precautions are essential when handling this substance, as it can pose serious health hazards if ingested or inhaled. Overall, [1,1′-Biphenyl]-4,4′-diamine hydrochloride is a compound of interest in both industrial applications and toxicological studies.

Formula: C₁₂H₁₂N₂·2ClH

InChI: InChI=1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H

InChI key: InChIKey=RUAXWVDEYJEWRY-UHFFFAOYSA-N

SMILES: NC1=CC=C(C=C1)C2=CC=C(N)C=C2.Cl

Synonyms:

• Benzidine hydrochloride
• Biphenyl-4,4'-Diaminato Hydrochloride (1:1)
• Biphenyl-4,4'-Diamine Dihydrochloride
• [1,1′-Biphenyl]-4,4′-diamine hydrochloride (1:2)
• [1,1′-Biphenyl]-4,4′-diamine, dihydrochloride
• Benzidine, dihydrochloride

Biphenyl-4,4'-diamine Dihydrochloride (Benzidine Dihydrochloride)

Controlled Product

CAS: 531-85-1

Formula: C₁₂H₁₂N₂ClH

Color and Shape: Neat

Molecular weight: 257.16

Ref: 86-MM0548.05

Phenylbutazone Impurity E

CAS: 531-85-1

Formula: C₁₂H₁₂N₂·2HCl

Molecular weight: 184.24 2x36.46

Ref: 4Z-P-346

Benzidinedihydrochloride

Controlled Product

CAS: 531-85-1

Benzidinedihydrochloride is a chemical compound that is used as a marker for chromatographic analysis. It has been shown to have genotoxic activity and carcinogenic potential. Benzidinedihydrochloride inhibits human DNA polymerase alpha, beta and gamma, which are enzymes involved in DNA synthesis. It also inhibits the enzyme activities of other proteins such as RNA polymerase II, ribonuclease H1, collagenase and alkaline phosphatase. The reaction solution is composed of benzidine hydrochloride (0.04 g), potassium chloride (0.2 g) and sodium hydroxide (0.02 g).

Formula: C₁₂H₁₄Cl₂N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 257.16 g/mol

Ref: 3D-FB147203