CAS 53101-49-8

(R)-(+)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-C

Description:

(R)-(+)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-C, commonly known as a derivative of tocopherol, is a naturally occurring compound with antioxidant properties. It is characterized by its chroman structure, which includes a saturated six-membered ring containing an oxygen atom. The presence of multiple methyl groups at the 2, 5, and 7 positions contributes to its lipophilicity and stability, enhancing its ability to scavenge free radicals. The hydroxyl group at the 6-position is crucial for its biological activity, as it facilitates interactions with cellular membranes and other biomolecules. This compound is often studied for its potential health benefits, particularly in relation to its role in protecting cells from oxidative stress and its implications in various diseases. Its chirality, indicated by the (R)- configuration, can influence its biological activity and interactions with enzymes and receptors. Overall, this substance is significant in both nutritional biochemistry and pharmacology, with ongoing research into its therapeutic applications.

Formula: C₁₄H₁₈O₄

InChI: InChI=1/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)/t14-/m1/s1

SMILES: Cc1c(C)c2c(CC[C@](C)(C(=O)O)O2)c(C)c1O

Synonyms:

• (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
• (2R)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromene-2-carboxylic acid
• Trolox (R)-Isomer
• (R)-Trolox D5
• Trolox Impurity 1 (Trolox (R)-Isomer)
• (2R)-2,5,7,8-Tetramethyl-6-hydroxychroman-2-carboxylic acid
• (R)-Trolox
• (2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
• 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2R)-
• (R)-(+)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-C
• (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 98%

(R)-(+)-6-Hydroxy-2,5,7,8-Tetramethylchroman-2-Carboxylic Acid

CAS: 53101-49-8

Formula: C₁₄H₁₈O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 250.2903

Ref: IN-DA003C5R

(R)-Trolox

CAS: 53101-49-8

(R)-Trolox

Purity: ≥98%

Molecular weight: 250.29g/mol

Ref: 54-BUP17913

(R)-Trolox

CAS: 53101-49-8

(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.

Formula: C₁₄H₁₈O₄

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 250.29

Ref: TM-T12645

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

CAS: 53101-49-8

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (HMCA) is a supplement that is used to treat cancer. HMCA is an acetyl donor and can be used as a substitute for erythromycin. HMCA was shown to inhibit the growth of human breast cancer cells in culture by reacting with lorazepam and lipase to form a reactive intermediate. This compound has been immobilized on ion-exchange resin for use in biodegradable materials and can be used for the treatment of chronic obstructive pulmonary disease (COPD).

Formula: C₁₄H₁₈O₄

Purity: Min. 95%

Molecular weight: 250.29 g/mol

Ref: 3D-DCA10149

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

CAS: 53101-49-8

Molecular weight: 250.2940063

Ref: 10-F865998

(R)-Trolox

Controlled Product

CAS: 53101-49-8

Applications (R)-Trolox is used in synthesis of vitamin E analogs.
References Dong, L., et al.: J. Biol. Chem., 286, 3717 (2011);

Formula: C₁₄H₁₈O₄

Color and Shape: Neat

Molecular weight: 250.29

Ref: TR-T892565