CAS 53109-32-3
:Histidylproline diketopiperazine
Description:
Histidylproline diketopiperazine, identified by its CAS number 53109-32-3, is a cyclic dipeptide that consists of two amino acids: histidine and proline. This compound is characterized by its unique diketopiperazine structure, which features a cyclic arrangement of the peptide bond, contributing to its stability and potential biological activity. The presence of histidine, an amino acid with an imidazole side chain, imparts properties such as the ability to participate in hydrogen bonding and metal ion coordination, while proline contributes to the rigidity of the peptide backbone due to its cyclic structure. Histidylproline diketopiperazine may exhibit various biological activities, including antioxidant properties and potential roles in cellular signaling. Its solubility in water and organic solvents can vary, influencing its applications in biochemical research and potential therapeutic uses. Overall, this compound represents a fascinating area of study within peptide chemistry, with implications for understanding protein structure and function.
Formula:C11H14N4O2
InChI:InChI=1S/C11H14N4O2/c16-10-9-2-1-3-15(9)11(17)8(14-10)4-7-5-12-6-13-7/h5-6,8-9H,1-4H2,(H,12,13)(H,14,16)/t8-,9-/m0/s1
InChI key:InChIKey=NAKUGCPAQTUSBE-IUCAKERBSA-N
SMILES:O=C1N2[C@](C(=O)N[C@H]1CC3=CN=CN3)(CCC2)[H]
Synonyms:- (3S,8aS)-3-(1H-imidazol-5-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
- (3S,8aS)-Hexahydro-3-(1H-imidazol-4-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione
- (3S,9aS)-3-(1H-imidazol-5-ylmethyl)tetrahydro-2H-pyrido[1,2-a]pyrazine-1,4(3H,6H)-dione
- 3-(1H-imidazol-5-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
- Cyclo(<span class="text-smallcaps">L</smallcap>-histidyl-<smallcap>L</span>-proline)
- Cyclo(histidyl-proline)
- Cyclo(prolylhistidine)
- Histidylproline - Piperazine-2,3-Dione (1:1)
- Histidylproline diketopiperazine
- Histidylproline dioxopiperazine
- Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-imidazol-4-ylmethyl)-, (3S,8aS)-
- Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-imidazol-4-ylmethyl)-, (3S-trans)-
- See more synonyms
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Found 9 products.
Cyclo(-His-Pro)
CAS:<p>Cyclo(His-Pro), a diketopiperazine showing various biological effects in the CNS, as well as endocrine effects, has been isolated from several mammalian tissues. In some cases, it has been identified as a degradation product of thyrotropin-releasing hormone (TRH). In the presence of zinc ions, cyclo(His-Pro) showed hypoglycemic effects and induced body weight reduction in rats.</p>Formula:C11H14N4O2Purity:> 99%Color and Shape:Whitish PowderMolecular weight:234.26Protirelin EP Impurity E
CAS:Formula:C11H14N4O2Color and Shape:White To Off-White SolidMolecular weight:234.26Cyclo(his-pro)
CAS:<p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>Formula:C11H14N4O2Purity:99.87%Color and Shape:SolidMolecular weight:234.25Cyclo(L-His-L-Pro)
CAS:<p>Cyclo(L-His-L-Pro) is a dipeptide molecule that is part of the thyroid hormone thyrotropin-releasing hormone. It has been shown to have physiological effects on experimental models, such as increased thyrotropin release and decreased calcium levels in cells. Cyclo(L-His-L-Pro) is synthesized by the enzyme prohormone convertase in the cytosol of cells. The cyclic structure of this molecule is due to intermolecular hydrogen bonding between His and Pro residues. This peptide can be metabolized into a number of metabolites, including cyclic, diketopiperazines.</p>Formula:C11H14N4O2Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:234.25 g/molCyclo(L-histidyl-L-proline)
CAS:Controlled ProductFormula:C11H14N4O2Color and Shape:NeatMolecular weight:234.255
