CAS 53185-12-9

Fagomine

Description:

Fagomine is a naturally occurring alkaloid derived from the plant species of the genus Fagopyrum, commonly known as buckwheat. It is characterized by its unique chemical structure, which includes a pyrrolidine ring, contributing to its biological activity. Fagomine has garnered interest due to its potential health benefits, particularly in the context of glycemic control and its ability to modulate carbohydrate metabolism. It acts as a glycosidase inhibitor, which may help in reducing the absorption of carbohydrates in the intestine, thus influencing blood sugar levels. Additionally, Fagomine has been studied for its prebiotic properties, promoting beneficial gut microbiota. Its safety profile and low toxicity make it a candidate for dietary supplements and functional foods. The compound is typically found in various concentrations in buckwheat and has been the subject of research for its potential therapeutic applications, including its role in managing diabetes and obesity. Overall, Fagomine represents a promising area of study in nutritional biochemistry and pharmacology.

Formula: C₆H₁₃NO₃

InChI: InChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5-,6-/m1/s1

InChI key: InChIKey=YZNNBIPIQWYLDM-HSUXUTPPSA-N

SMILES: C(O)[C@@H]1[C@@H](O)[C@H](O)CCN1

Synonyms:

• (2R,3R,4R)-2-(Hydroxymethyl)-3,4-piperidinediol
• 1,2,5-Trideoxy-1,5-imino-<span class="text-smallcaps">D</span>-arabino-hexitol
• 3,4-Piperidinediol, 2-(hydroxymethyl)-, [2R-(2α,3β,4α)]-
• 3,4-piperidinediol, 2-(hydroxymethyl)-, (2R,3R,4R)-
• <span class="text-smallcaps">D</span>-Fagomine
• Fagomine
• 1,2,5-Trideoxy-1,5-imino-D-arabino-hexitol
• (2R,3R,4R)-2-(Hydroxymethyl)piperidine-3,4-diol

Fagomine

CAS: 53185-12-9

Formula: C₆H₁₃NO₃

Purity: %

Color and Shape: Solid

Molecular weight: 147.1723

Ref: IN-DA00DB65

(2R,3R,4R)-2-(Hydroxymethyl)piperidine-3,4-diol

CAS: 53185-12-9

(2R,3R,4R)-2-(Hydroxymethyl)piperidine-3,4-diol

Purity: 98%

Molecular weight: 147.17g/mol

Ref: 54-OR1066357

Fagomine

CAS: 53185-12-9

Formula: C₆H₁₃NO₃

Purity: 95%~99%

Molecular weight: 147.174

Ref: BP-BP2176

Fagomine

CAS: 53185-12-9

Fagomine (D-Fagomine) is a glycosidase inhibitor, an analog of 1-deoxynojirimycin (DNJ), with hypoglycemic activity.

Formula: C₆H₁₃NO₃

Purity: 98.97%

Color and Shape: Solid

Molecular weight: 147.17

Ref: TM-TQ0298

Fagomine-d2

CAS: 53185-12-9

Formula: C₆H₁₁D₂NO₃

Molecular weight: 149.19

Ref: 4Z-F-103002

Fagomine

CAS: 53185-12-9

Formula: C₆H₁₃NO₃

Molecular weight: 147.18

Ref: 4Z-F-103001

Fagomine

CAS: 53185-12-9

Fagomine is a hypoglycemic agent with antimicrobial properties. It is an alpha-mannosidase inhibitor, which prevents the release of glucose from glycogen by inhibiting an enzyme in the glycosylation pathway. The molecular docking analysis shows that fagomine binds to the active site of mitochondrial membrane potential complex I and inhibits its catalytic activity. Fagomine also has a risk of causing metabolic disorders, such as hyperglycemia, hyperinsulinemia, and hyperlipidemia. Studies have shown that fagomine can be used to treat hyperglycemia in both type 1 and type 2 diabetes mellitus patients.

Formula: C₆H₁₃NO₃

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 147.17 g/mol

Ref: 3D-MF03611

fagomine

CAS: 53185-12-9

Purity: 98+%

Molecular weight: 147.173996

Ref: 10-F866544

Fagomine-13C,d2

Controlled Product

CAS: 53185-12-9

Formula: CC₅D₂H₁₁NO₃

Color and Shape: Neat

Molecular weight: 150.177

Ref: TR-F101057

Fagomine

Controlled Product

CAS: 53185-12-9

Formula: C₆H₁₃NO₃

Color and Shape: Neat

Molecular weight: 147.172

Ref: TR-F101055