CAS 532-27-4

2-Chloroacetophenone

Description:

2-Chloroacetophenone, with the CAS number 532-27-4, is an organic compound that belongs to the class of aromatic ketones. It features a chloro substituent on the second carbon of the acetophenone structure, which consists of a phenyl group attached to an acetyl group. This compound is typically a colorless to pale yellow liquid with a characteristic odor. It is moderately soluble in water and more soluble in organic solvents such as ethanol and ether. 2-Chloroacetophenone is known for its use in organic synthesis and as a reagent in various chemical reactions. Additionally, it has applications in the production of pharmaceuticals and agrochemicals. Due to its potential irritant properties, it should be handled with care, as it can cause skin and respiratory irritation upon exposure. Proper safety measures, including the use of personal protective equipment, are recommended when working with this compound.

Formula: C₈H₇ClO

InChI: InChI=1S/C8H7ClO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2

InChI key: InChIKey=IMACFCSSMIZSPP-UHFFFAOYSA-N

SMILES: C(CCl)(=O)C1=CC=CC=C1

Synonyms:

• (2-Chloro-1-oxoethyl)benzene
• (Chloroacetyl)benzene
• 1-Phenyl-2-chloro-1-ethanone
• 2-Chloracetophenon
• 2-Chloro-1-phenyl-1-ethanone
• 2-Chloro-1-phenylethanone
• 2-Chloroacetophenone
• 2-Cloroacetofenona
• Acetophenone, 2-chloro-
• Acetophenone, Chloro-
• Acetophenone, α-chloro-
• Agent CNB
• Agent CNC
• Benzoylmethyl chloride
• CAF
• CAP
• CN
• CN (lacrimator)
• CNB
• CNB (chemical warfare agent)
• CNC
• Chloracetophenone
• Chloroacetophenone
• Chloromethyl phenyl ketone
• Mace
• Mace (lacrimator)
• Nsc 41666
• Phenacyl chloride
• Phenyl chloromethyl ketone
• Α-Chloracetophenon
• α-Chloroacetophenone
• ω-Chloroacetophenone
• Ethanone, 2-chloro-1-phenyl-

2-Chloroacetophenone

Controlled Product

CAS: 532-27-4

2-Chloroacetophenone is a chemical that has been shown to be an effective inhibitor of the enzyme form of the human acetylcholinesterase. It is used in experimental studies for its ability to inhibit the activity of other enzymes such as polymerase chain, which is involved in DNA replication. 2-Chloroacetophenone has also been shown to have anti-cancer properties, inhibiting skin cancer cells and cancer cells derived from cardiac tissue. The drug also has anti-inflammatory properties and can be used for the treatment of arthritis. 2-Chloroacetophenone's toxicity has been studied extensively and it does not appear to affect glomerular filtration rate or body mass index significantly, although it may affect receptor activity.

Formula: C₈H₇ClO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 154.59 g/mol

Ref: 3D-FC00929

2-Chloroacetophenone

Controlled Product

CAS: 532-27-4

Applications 2-Chloroacetophenone is a chemical warfare agent commonly known as ‘Mace’ affects the oral, nasal and conjunctival mucous membranes also causing loss of balance and disorientation. Also a chemical building block for organic synthesis.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.
E0
References Ballantyne, B. et al.: Arch. Toxicol., 40, 75 (1978);

Formula: C₈H₇ClO

Color and Shape: Neat

Molecular weight: 154.59

Ref: TR-C363445

2-Chloroactophenone pure, 97%

CAS: 532-27-4

Formula: C₈H₇ClO

Purity: min. 97%

Color and Shape: White to pale yellow, Solid

Molecular weight: 154.60

Ref: SR-70179