CAS 5321-49-3

1-(2-Phenylethyl)piperazine

Description:

1-(2-Phenylethyl)piperazine, with the CAS number 5321-49-3, is an organic compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. This compound features a phenylethyl group attached to one of the nitrogen atoms of the piperazine, contributing to its unique properties. It is typically a colorless to pale yellow liquid or solid, depending on the specific conditions and purity. The substance is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its ability to interact with various biological targets. Its structure allows for the possibility of forming hydrogen bonds, which can influence its solubility and reactivity. Additionally, 1-(2-Phenylethyl)piperazine may exhibit psychoactive properties, making it of interest in neuropharmacology. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if ingested or inhaled. Proper laboratory practices should be followed when working with this compound.

Formula: C₁₂H₁₈N₂

InChI: InChI=1S/C12H18N2/c1-2-4-12(5-3-1)6-9-14-10-7-13-8-11-14/h1-5,13H,6-11H2

InChI key: InChIKey=LKUAPSRIYZLAAO-UHFFFAOYSA-N

SMILES: C(CN1CCNCC1)C2=CC=CC=C2

Synonyms:

• 1-(2-Cyclohexylethyl)Piperazinediium
• 1-(Phenethyl)piperazine
• 1-Phenethylpiperazine
• 1-Phenylethyl Piperazine
• 4-Phenethylpiperazine
• N-(2-Phenylethyl)piperazine
• N-(β-Phenylethyl)piperazine
• N-Phenethylpiperazine
• Piperazine, 1-(2-phenylethyl)-
• Piperazine, 1-phenethyl-
• 1-(2-Phenylethyl)piperazine

1-(2-Phenylethyl)piperazine, 98%

CAS: 5321-49-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₂H₁₈N₂

Purity: 98%

Color and Shape: Liquid, Clear colorless to yellow

Molecular weight: 190.29

Ref: 02-B25158

1-Phenethylpiperazine

CAS: 5321-49-3

Formula: C₁₂H₁₈N₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 190.2847

Ref: IN-DA003CVJ

1-(2-Phenylethyl)piperazine

CAS: 5321-49-3

1-(2-Phenylethyl)piperazine

Formula: C₁₂H₁₈N₂

Purity: 98%

Color and Shape: clear liquid

Molecular weight: 190.28g/mol

Ref: 54-OR6849

1-(2-Phenylethyl)piperazine

CAS: 5321-49-3

Formula: C₁₂H₁₈N₂

Purity: 98%(HPLC);RG

Molecular weight: 190.29

Ref: 10-F009824

1-(2-Phenylethyl)piperazine

Controlled Product

CAS: 5321-49-3

Applications 1-(2-Phenylethyl)piperazine is used to prepare non-imidazole human histamine H4 receptor antagonists. it is also used to synthesize imidazopyridine derivatives as inhibitors of Aurora kinases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jablonowski, J., et al.: J. Med. Chem., 46, 3957 (2003); Bavetsias, V., et al.: Bioorg. Med. Chem. Lett., 17, 6567 (2007)

Formula: C₃₂H₅₈O₅Si

Color and Shape: Neat

Molecular weight: 550.885

Ref: TR-P321325

1-(2-Phenylethyl)piperazine

Controlled Product

CAS: 5321-49-3

1-(2-Phenylethyl)piperazine is a potential drug for the treatment of insulin resistance. It has been shown to increase insulin sensitivity in mice and humans, as measured by glucose uptake rates, pharmacokinetic properties, and insulin sensitivity. This compound may be used in combination with other drugs to treat cancer or skin conditions. 1-(2-Phenylethyl)piperazine has also been shown to bind to the aminophenyl receptor, which is a G protein-coupled receptor that is involved in cell proliferation and apoptosis. The aminophenyl receptor also binds to multidrugs such as HIV protease inhibitors (e.g., indinavir), which suggests that it may have antitumor effects.

Formula: C₁₂H₁₈N₂

Purity: Min. 95%

Molecular weight: 190.28 g/mol

Ref: 3D-FP46415