CAS 5321-65-3

Piperazine, 1,4-bis[(3-methylphenyl)methyl]-, hydrochloride (1:2)

Description:

Piperazine, 1,4-bis[(3-methylphenyl)methyl]-, hydrochloride (1:2), with the CAS number 5321-65-3, is a chemical compound characterized by its piperazine core structure, which is a six-membered ring containing two nitrogen atoms. This compound features two 3-methylphenylmethyl substituents, enhancing its lipophilicity and potentially influencing its biological activity. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, which is advantageous for various applications, including pharmaceuticals. The presence of the methyl groups on the phenyl rings may contribute to its steric properties and affect its interaction with biological targets. Piperazine derivatives are often studied for their pharmacological properties, including anxiolytic and antidepressant effects. The compound's hydrochloride form indicates that it can exist as a stable crystalline solid, making it suitable for formulation in medicinal chemistry. Overall, this compound's unique structure and properties make it of interest in both research and potential therapeutic applications.

Formula: C₂₀H₂₆N₂·2ClH

InChI: InChI=1S/C20H26N2.2ClH/c1-17-5-3-7-19(13-17)15-21-9-11-22(12-10-21)16-20-8-4-6-18(2)14-20;;/h3-8,13-14H,9-12,15-16H2,1-2H3;2*1H

InChI key: InChIKey=RBZJAYKYBXBPIN-UHFFFAOYSA-N

SMILES: C(N1CCN(CC2=CC(C)=CC=C2)CC1)C3=CC(C)=CC=C3.Cl

Synonyms:

• Piperazine, 1,4-bis[(3-methylphenyl)methyl]-, hydrochloride (1:2)
• Piperazine, 1,4-bis(m-methylbenzyl)-, dihydrochloride

Meclizine Impurity 1 DiHCl

CAS: 5321-65-3

Formula: C₂₀H₂₆N₂·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 294.44 2*36.46

Ref: 4Z-M-407