CAS 53216-90-3

Griseoviridin

Description:

Griseoviridin is a natural compound classified as a polyene antibiotic, primarily derived from the fermentation of certain species of fungi, particularly those in the genus Penicillium. It exhibits antifungal properties and has been utilized in veterinary medicine, particularly for the treatment of fungal infections in animals. The compound is characterized by its complex molecular structure, which includes multiple conjugated double bonds that contribute to its biological activity. Griseoviridin is known for its ability to inhibit the growth of various fungi by interfering with their cellular processes. It is often used in the context of research and has been studied for its potential applications in treating fungal infections in humans, although its use in human medicine is limited. Additionally, safety and toxicity profiles are important considerations, as with many antibiotics, and its use is regulated in many regions. Overall, Griseoviridin represents an important compound in the field of mycology and pharmacology, highlighting the significance of natural products in developing therapeutic agents.

Formula: C₂₂H₂₇N₃O₇S

InChI: InChI=1S/C22H27N3O7S/c1-13-6-7-18-21(29)23-8-4-2-3-5-14(26)9-15(27)10-19-24-16(11-31-19)20(28)25-17(12-33-18)22(30)32-13/h2-5,7,11,13-15,17,26-27H,6,8-10,12H2,1H3,(H,23,29)(H,25,28)/b4-2+,5-3+,18-7-/t13-,14-,15-,17-/m1/s1

InChI key: InChIKey=UXWOXTQWVMFRSE-JCSRQJCQSA-N

SMILES: O=C1C=2N=C(OC2)C[C@H](O)C[C@H](O)/C=C/C=C/CNC(=O)\C=3\SC[C@@](N1)(C(=O)O[C@H](C)C/C3)[H]

Synonyms:

• (1S,9R,11S,12E,14E,19Z,22R)-9,11-Dihydroxy-22-methyl-6,23-dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentaene-3,18,24-trione
• Griseoviridin
• 6,23-Dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentaene-3,18,24-trione, 9,11-dihydroxy-22-methyl-, [1S-(1R*,9S*,11R*,12E,14E,19Z,22S*)]-
• 6,23-Dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentaene-3,18,24-trione, 9,11-dihydroxy-22-methyl-, (1S,9R,11S,12E,14E,19Z,22R)-
• 6,23-Dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosane, griseoviridin deriv.
• 6,23-Dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentaene-3,18,24-trione, 9,11-dihydroxy-22-methyl-, (1S,9R,11S,12Z,14Z,19Z,22R)-
• (1S,9S,11S,12E,14E,19Z,22R)-9,11-Dihydroxy-22-methyl-6,23-dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentene-3,8,24-trione
• Aids166753
• Aids-166753

Griseoviridin

CAS: 53216-90-3

Griseoviridin is a lactone antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria.

Color and Shape: Solid

Ref: TM-TN10110

Griseoviridin

CAS: 53216-90-3

Griseoviridin

Formula: C₂₂H₂₇N₃O₇S

Purity: By hplc: 100% (Typical Value in Batch COA)

Color and Shape: brownish solid

Molecular weight: 477.53g/mol

Ref: 54-BIBR1137

Griseoviridin

CAS: 53216-90-3

Griseoviridin is a medicinal compound that has shown promise as an anticancer agent. It is an analog of the natural product griseoviridin A, which was isolated from a fungus. Griseoviridin has been shown to inhibit the activity of kinases, which are enzymes that play a key role in cell cycle regulation and apoptosis. This inhibition leads to the selective killing of cancer cells, making it a potential treatment for various types of tumors. Griseoviridin also inhibits the activity of proteins involved in xylan degradation and has been shown to be effective against human cancer cell lines. Its potent anticancer activity makes it an attractive candidate for development as a new class of cancer therapeutics.

Formula: C₂₂H₂₇N₃O₇S

Purity: Min. 95%

Molecular weight: 477.5 g/mol

Ref: 3D-DCA21690