CAS 53267-01-9

Cibenzoline

Description:

Cibenzoline, with the CAS number 53267-01-9, is a chemical compound primarily recognized for its use as an antiarrhythmic agent. It belongs to the class of compounds known as benzodiazepines, which are characterized by their fused benzene and diazepine rings. Cibenzoline exhibits properties that allow it to modulate cardiac electrical activity, making it useful in the treatment of certain heart rhythm disorders. The compound is typically administered in its salt form, which enhances its solubility and bioavailability. Cibenzoline's mechanism of action involves the blockade of sodium channels, thereby stabilizing cardiac membranes and reducing excitability. It is important to note that, like many pharmacological agents, Cibenzoline may have side effects and contraindications, necessitating careful consideration in clinical use. Additionally, its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are crucial for understanding its therapeutic efficacy and safety profile. Overall, Cibenzoline represents a significant compound in the realm of cardiovascular pharmacotherapy.

Formula: C₁₈H₁₈N₂

InChI: InChI=1S/C18H18N2/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17/h1-10,16H,11-13H2,(H,19,20)

InChI key: InChIKey=IPOBOOXFSRWSHL-UHFFFAOYSA-N

SMILES: C1(C(C1)C=2NCCN2)(C3=CC=CC=C3)C4=CC=CC=C4

Synonyms:

• (RS)-Cibenzoline
• (±)-2-(2,2-Diphenylcyclopropyl)-2-imidazoline
• (±)-2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
• 1-(2-D2-Imidazolinyl)-2,2-diphenylcyclopropane
• 1H-imidazole, 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-
• 258-453-7
• Cifenline
• Ro 22-7796
• Up 33-901
• Cibenzoline

1H-Imidazole, 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-

CAS: 53267-01-9

Formula: C₁₈H₁₈N₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 262.3489

Ref: IN-DA00I9IC

Cibenzoline

CAS: 53267-01-9

Formula: C₁₈H₁₈N₂

Molecular weight: 262.36

Ref: 4Z-C-280001

Cibenzoline

CAS: 53267-01-9

Formula: C₁₈H₁₈N₂

Molecular weight: 262.35

Ref: 7W-GP1349

Cibenzoline

Controlled Product

CAS: 53267-01-9

Applications Cibenzoline acts as a highly active class I antiarrhythmic agent.
References Xie, C. et al.: Handbook. Metab. Pathway. Xenobio., 3, 1110 (2014);

Formula: C₁₈H₁₈N₂

Color and Shape: Neat

Molecular weight: 262.35

Ref: TR-C535723

Cibenzoline

CAS: 53267-01-9

Cibenzoline: antiarrhythmic, blocks KATP channels, minimizes LVPG, useful in hypertrophic cardiomyopathy studies.

Formula: C₁₈H₁₈N₂

Color and Shape: Solid

Molecular weight: 262.35

Ref: TM-T60428