CAS 53292-89-0

trans-4-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid

Description:

Trans-4-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid is an organic compound characterized by its cyclohexane ring structure, which features a carboxylic acid functional group and a tert-butoxycarbonyl (Boc) protecting group attached to an amino group. This compound is typically used in peptide synthesis and other organic synthesis applications due to the stability provided by the Boc group, which can be selectively removed under acidic conditions. The trans configuration indicates that the substituents on the cyclohexane ring are positioned opposite each other, influencing the compound's stereochemistry and reactivity. The presence of both the carboxylic acid and the amino group makes it an important intermediate in the synthesis of various pharmaceuticals and biologically active molecules. Additionally, the compound is likely to exhibit solubility in polar organic solvents, and its properties can be influenced by the pH of the environment, particularly due to the acidic nature of the carboxylic acid group. Overall, this compound is significant in the field of medicinal chemistry and organic synthesis.

Formula: C₁₂H₂₁NO₄

InChI: InChI=1/C12H21NO4/c1-12(2,3)17-11(16)13-9-6-4-8(5-7-9)10(14)15/h8-9H,4-7H2,1-3H3,(H,13,16)(H,14,15)/t8-,9-

InChI key: InChIKey=KXMRDHPZQHAXML-KYZUINATNA-N

SMILES: C(O)(=O)[C@H]1CC[C@H](NC(OC(C)(C)C)=O)CC1

Synonyms:

• Boc-1,4-Trans-Achc-OH
• Boc-Trans-4-Aminocyclohexanecarboxylic Acid
• Boc-trans-4-aminocyclohexane-1-carboxylic acid
• Cyclohexanecarboxylic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Trans-
• Trans-4-(Boc-Amino)Cyclohexanecarboxylic Acid
• trans-4-(tert-Butoxycarbonylamino)cyclohexane-1-carboxylic acid
• trans-4-[(N-tert-butoxycarbonyl)amino]-1-cyclohexanecarboxylic acid
• trans-4-[(tert-Butoxycarbonyl)amino]cyclohexane-1-carboxylic acid
• trans-4-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid
• trans-4-[(tert-Butyloxycarbonyl)amino]cyclohexanecarboxylic acid
• trans-4-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclohexanecarboxylic acid

trans-4-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid

CAS: 53292-89-0

Formula: C₁₂H₂₁NO₄

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 243.30

Ref: 3B-B3250

BOC-1,4-TRANS-ACHC-OH

CAS: 53292-89-0

Formula: C₁₂H₂₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 243.2994

Ref: IN-DA003OF8

4-tert-Butoxycarbonylamino-cyclohexanecarboxylic acid

CAS: 53292-89-0

4-tert-Butoxycarbonylamino-cyclohexanecarboxylic acid

Purity: 98%

Molecular weight: 243.30g/mol

Ref: 54-OR97605

trans-4-(Boc-amino)cyclohexanecarboxylic acid

CAS: 53292-89-0

Formula: C₁₂H₂₁NO₄

Molecular weight: 243.30

Ref: 7W-GM1877

Boc-trans-4-Aminocyclohexanecarboxylic acid

CAS: 53292-89-0

Formula: C₁₂H₂₁NO₄

Purity: 97%

Color and Shape: Solid, White to very pale yellow crystal powder

Molecular weight: 243.303

Ref: 10-F048415

Boc-trans-4-aminocyclohexanecarboxylic acid

Controlled Product

CAS: 53292-89-0

Applications Boc-trans-4-aminocyclohexanecarboxylic acid is a reagent to synthesize N-myristoyltransferase and CD38 inhibitors.
References Yamazaki, K., et al.: Bioorg. Med. Chem 13, 2509 (2005); Haffner, C. D., et al.: J. Med. Chem 58, 3548 (2015)

Formula: C₁₂H₂₁NO₄

Color and Shape: Neat

Molecular weight: 243.3

Ref: TR-B667860