CAS 533-45-9: Clomethiazole

Description: Clomethiazole, with the CAS number 533-45-9, is a thiazole derivative primarily recognized for its sedative and anxiolytic properties. It appears as a white to off-white crystalline powder and is soluble in water and alcohol, which facilitates its use in various formulations. The compound acts as a central nervous system depressant, often utilized in the management of alcohol withdrawal symptoms and as a sedative in certain medical contexts. Clomethiazole functions by enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits neuronal excitability, thereby promoting relaxation and sleep. However, its use is associated with potential side effects, including respiratory depression and dependence, necessitating careful monitoring. Due to its pharmacological profile, clomethiazole is typically prescribed with caution, and its use may be restricted in some regions. Overall, while effective in specific therapeutic scenarios, the safety profile of clomethiazole requires thorough consideration in clinical practice.

Formula: C₆H₈ClNS

InChI: InChI=1S/C6H8ClNS/c1-5-6(2-3-7)9-4-8-5/h4H,2-3H2,1H3

InChI key: InChIKey=PCLITLDOTJTVDJ-UHFFFAOYSA-N

SMILES: ClCCC=1SC=NC1C

Synonyms:

• 4-Methyl-5-(β-chloroethyl)thiazole
• 5-(2-Chloroethyl)-4-Methyl-1,3-Thiazole Hydrochloride
• 5-(2-Chloroethyl)-4-Methylthiazole
• 5-(β-Chloroethyl)-4-methylthiazole
• Chlorethiazol
• Chlorethiazole
• Chlormethiazol
• Chlormethiazole
• Clomethiazolum
• Distraneurin
• Emineurina
• Somnevrin
• Thiazole, 5-(2-chloroethyl)-4-methyl-
• Clomethiazole

Chlormethiazole Hydrochloride

CAS: 533-45-96001-74-7

• Formula: C₆H₈ClNS·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 198.11

Clomethiazole

CAS: 533-45-9

• Formula: C₆H₈ClNS
• Purity: 99%
• Color and Shape: Liquid
• Molecular weight: 161.6524

Clomethiazole

CAS: 533-45-9

Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It …

• Formula: C₆H₈ClNS
• Purity: 99.06%
• Color and Shape: Solid
• Molecular weight: 161.65

Clomethiazole

CAS: 533-45-9

• Purity: 97%
• Molecular weight: 161.65g/mol

5-(2-Chloroethyl)-4-methylthiazole

CAS: 533-45-9

• Purity: 97.0%
• Color and Shape: Solid
• Molecular weight: 161.64999389648438

Clomethiazole-d7

CAS: 533-45-9

• Formula: C₆HD₇ClNS
• Molecular weight: 168.69

Clomethiazolum

CAS: 533-45-9

• Formula: C₆H₈ClNS
• Molecular weight: 161.65

Chlormethiazole

CAS: 533-45-9

Sedative and hypnotic; used in treatment of acute alcohol withdrawal

• Formula: C₆H₈ClNS
• Purity: Min. 95%
• Color and Shape: Colorless Powder
• Molecular weight: 161.65 g/mol

Clomethiazolum

CAS: 533-45-9

Applications Clomethiazolum is a drug which is structurally related to thiamine (vitamin B1) but acts …

• Formula: C₆H₈ClNS
• Color and Shape: Neat
• Molecular weight: 161.65

Clomethiazolum-d4

CAS: 533-45-9

Applications Clomethiazolum-d4 is derived from Formamide (F691480), which is a compound that used in biochemistry …

• Formula: C₆D₄H₄ClNS
• Color and Shape: Neat
• Molecular weight: 165.677