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CAS 53332-78-8

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5-(trifluoromethyl)thiophene-3-ol

Description:
5-(Trifluoromethyl)thiophene-3-ol is an organic compound characterized by its thiophene ring, which is a five-membered aromatic heterocycle containing sulfur. The presence of a trifluoromethyl group (-CF3) at the 5-position significantly influences its chemical properties, enhancing its lipophilicity and potentially its reactivity. The hydroxyl group (-OH) at the 3-position contributes to its polarity and can participate in hydrogen bonding, affecting its solubility in various solvents. This compound is of interest in various fields, including pharmaceuticals and materials science, due to its unique electronic properties and potential applications in synthesis. Additionally, the trifluoromethyl group is known to impart stability and influence the compound's interaction with biological systems. Overall, 5-(trifluoromethyl)thiophene-3-ol exhibits a combination of aromaticity, heteroatom presence, and functional groups that make it a versatile building block in organic synthesis and a subject of study in chemical research.
Formula:C5H3F3OS
InChI:InChI=1/C5H3F3OS/c6-5(7,8)4-1-3(9)2-10-4/h1-2,9H
SMILES:c1c(csc1C(F)(F)F)O
Synonyms:
  • 3-Thiopheneol, 5-(trifluoromethyl)-
  • 1,3-Thiazol-2-Ylmethanamine Dihydrochloride
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