CAS 5334-23-6

Tisopurine

Description:

Tisopurine, with the CAS number 5334-23-6, is a purine analog that is primarily used as an immunosuppressive agent in the treatment of certain autoimmune diseases and in organ transplantation. It functions by inhibiting purine metabolism, which ultimately affects DNA synthesis and cell proliferation, particularly in lymphocytes. Tisopurine is known for its ability to modulate the immune response, making it beneficial in conditions where the immune system is overactive. The compound is typically administered orally and is metabolized in the liver, where it can be converted into active metabolites that exert therapeutic effects. Its pharmacokinetics can be influenced by genetic factors, particularly variations in enzymes involved in its metabolism, which can affect efficacy and toxicity. Common side effects may include gastrointestinal disturbances and bone marrow suppression, necessitating careful monitoring during treatment. Overall, Tisopurine represents a valuable option in the management of specific medical conditions requiring immunosuppression.

Formula: C₅H₄N₄S

InChI: InChI=1S/C5H4N4S/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)

InChI key: InChIKey=PYAOPMWCFSVFOT-UHFFFAOYSA-N

SMILES: S=C1C2=C(NC=N1)NN=C2

Synonyms:

• 1,2-Dihydropyrazolo[3,4-d]pyrimidine-4-thione
• 1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-thione
• 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-thione
• 1H,4H,5H-Pyrazolo[3,4-d]pyrimidine-4-thione
• 1H,4H,7H-Pyrazolo[3,4-d]pyrimidine-4-thione
• 1H-Pyrazolo[3,4-d]pyrimidine-4(5H)-thione
• 1H-Pyrazolo[3,4-d]pyrimidine-4-thiol
• 1H-Pyrazolo[3,4-d]pyrimidine-4-thiol hemihydrate
• 1H-pyrazolo[3,4-d]pyrimidine-4-thiolate
• 4-Mercapto-1H-pyrazolo[3,4-d]pyrimidine
• 4-Mercaptopyrazole(3,4d)pyrimidine
• 4-Mercaptopyrazolo[3,4-d]pyrimidine
• 4H-Pyrazolo[3,4-d]pyrimidine-4-thione, 1,5-dihydro-
• 5H-Pyrazolo[3,4-d]pyrimidine-4-thione
• 8-Aza-7-deaza-6-thiopurine
• Allopurinol, thio-
• MPP (pharmaceutical)
• Mercaptopyrazolepyrimidine
• NSC 1392
• Thiopurinol

1H-Pyrazolo[3,4-d]pyrimidine-4-thiol

CAS: 5334-23-6

Formula: C₅H₄N₄S

Molecular weight: 152.1771

Ref: IN-DA003LLZ

1H-pyrazolo[3,4-d]pyrimidine-4-thiol

CAS: 5334-23-6

Formula: C₅H₄N₄S

Purity: 95.0%

Molecular weight: 152.18

Ref: 10-F496496

Tisopurine

CAS: 5334-23-6

Tisopurine is a drug used in the treatment of gout in some countries. It reduces uric acid production through inhibiting an early stage in its production.

Formula: C₅H₄N₄S

Color and Shape: Solid

Molecular weight: 152.18

Ref: TM-T71808