CAS 53363-89-6

boc-N-methyl-L-leucine

Description:

Boc-N-methyl-L-leucine, with the CAS number 53363-89-6, is a derivative of the amino acid leucine, characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group on the amino group and a methyl group on the nitrogen. This compound is typically used in peptide synthesis as a protected amino acid, facilitating the formation of peptide bonds while preventing unwanted reactions at the amino group. It is a white to off-white solid, soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but generally insoluble in water. The Boc group is commonly employed in organic synthesis due to its stability under basic conditions and ease of removal under acidic conditions, making it a valuable tool in the synthesis of complex molecules. The presence of the N-methyl group can influence the steric and electronic properties of the molecule, potentially affecting its reactivity and interactions in biological systems. Overall, Boc-N-methyl-L-leucine serves as an important intermediate in the development of pharmaceuticals and biologically active compounds.

Formula: C₁₂H₂₃NO₄

InChI: InChI=1/C12H23NO4/c1-8(2)7-9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t9-/m0/s1

SMILES: CC(C)C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C

Synonyms:

• Boc-N-Me-Leu-OH
• N-alpha-t-butyloxycabonyl-N-alpha-Methyl-L-leucine
• N-(tert-butoxycarbonyl)-N-methylleucine
• N-(tert-butoxycarbonyl)-N-methyl-L-leucine
• Tyr(me)
• Boc-N-Methyl Leucine

L-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-

CAS: 53363-89-6

Formula: C₁₂H₂₃NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 245.3153

Ref: IN-DA00I9J2

Boc-N-Me-Leu-OH

CAS: 53363-89-6

Formula: C₁₂H₂₃NO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 245.32

Ref: 7W-GM3568

Boc-N-Me-Leu-OH

CAS: 53363-89-6

Boc-N-Me-Leu-OH

Purity: 98%

Molecular weight: 245.32g/mol

Ref: 54-OR1012533

Boc-N-Me-Leu-OH

CAS: 53363-89-6

Formula: C₁₂H₂₃NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 245.32

Ref: 3B-B6363

Boc-N-methyl-L-leucine

CAS: 53363-89-6

Formula: C₁₂H₂₃NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 245.319

Ref: 10-F044540

Boc-N-methyl-L-leucine

CAS: 53363-89-6

Boc-N-methyl-L-leucine is a peptidyl nucleobase that has been shown to inhibit tumor cell growth and induce tumor regression in animal models. It is an amide of leucine and the antibiotic aminouracil, which is a guanine analogue. Boc-N-methyl-L-leucine has also shown to inhibit tumor growth by inhibiting mitochondrial membrane potential, which may lead to cell death in cancer cells. This compound has been shown to be effective against both solid tumors and leukemia cell lines. Boc-N-methyl-L-leucine also inhibits the proliferation of human prostate cancer cells by blocking the synthesis of nucleic acids and proteins.

Formula: C₁₂H₂₃NO₄

Purity: Min. 95%

Molecular weight: 245.32 g/mol

Ref: 3D-FB47462