CAS 53472-18-7
:5-Bromo-8-quinolinamine
Description:
5-Bromo-8-quinolinamine is an organic compound characterized by its quinoline structure, which consists of a bicyclic aromatic system containing a nitrogen atom. This compound features a bromine substituent at the 5-position and an amino group at the 8-position of the quinoline ring. It is typically a solid at room temperature and may exhibit a range of colors depending on its purity and crystalline form. The presence of the bromine atom can influence its reactivity, making it useful in various chemical reactions, including nucleophilic substitutions and coupling reactions. The amino group contributes to its basicity and potential for forming hydrogen bonds, which can enhance its solubility in polar solvents. 5-Bromo-8-quinolinamine is of interest in medicinal chemistry and materials science, as it may possess biological activity and can serve as a precursor for the synthesis of more complex compounds. Safety data should be consulted for handling, as with many chemical substances, it may pose health risks if not managed properly.
Formula:C9H7BrN2
InChI:InChI=1S/C9H7BrN2/c10-7-3-4-8(11)9-6(7)2-1-5-12-9/h1-5H,11H2
InChI key:InChIKey=GEABITRRZOHARP-UHFFFAOYSA-N
SMILES:BrC=1C2=C(C(N)=CC1)N=CC=C2
Synonyms:- 5-Bromoquinolin-8-Amine
- 8-Amino-5-bromoquinoline
- 8-Quinolinamine, 5-bromo-
- 5-Bromo-8-quinolinamine
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Found 4 products.
5-Bromo-quinolin-8-ylamine
CAS:Formula:C9H7BrN2Purity:97%Color and Shape:SolidMolecular weight:223.06935-Bromo-quinolin-8-ylamine
CAS:Formula:C9H7BrN2Purity:97%Color and Shape:SolidMolecular weight:223.0735-Bromoquinolin-8-amine
CAS:<p>5-Bromoquinolin-8-amine is a topoisomerase inhibitor that can be used as an antitumor agent. It has been shown to inhibit the growth of tumor cell lines and suppress the growth of colon carcinoma cells in rats and human colon carcinomas in mice. 5-Bromoquinolin-8-amine interacts with DNA, specifically inhibiting the formation of supercoiled DNA. This interaction may lead to the inhibition of tumor cell growth. 5-Bromoquinolin-8-amine also inhibits protein synthesis by interacting with proteins at the ribosomal level, leading to inhibited cell growth.</p>Formula:C9H7BrN2Purity:Min. 95%Molecular weight:223.07 g/mol
