CAS 535-52-4

2-Fluoro-5-(trifluoromethyl)aniline

Description:

2-Fluoro-5-(trifluoromethyl)aniline is an aromatic amine characterized by the presence of a fluorine atom at the second position and a trifluoromethyl group at the fifth position of the aniline ring. Its molecular formula is C7H5F4N, indicating that it contains seven carbon atoms, five hydrogen atoms, four fluorine atoms, and one nitrogen atom. This compound is typically a colorless to pale yellow liquid or solid, depending on its physical state at room temperature. It exhibits properties typical of both aromatic compounds and amines, including potential reactivity due to the electron-withdrawing effects of the trifluoromethyl group, which can influence its chemical behavior and interactions. 2-Fluoro-5-(trifluoromethyl)aniline is often used in organic synthesis and may serve as an intermediate in the production of pharmaceuticals, agrochemicals, and other fluorinated compounds. Safety precautions should be taken when handling this substance, as it may pose health risks, including toxicity and environmental hazards.

Formula: C₇HClF₄O₂

InChI: InChI=1/C7HClF4O2/c8-2-3(9)1(7(13)14)4(10)6(12)5(2)11/h(H,13,14)

SMILES: c1(c(c(c(c(c1F)F)F)Cl)F)C(=O)O

Synonyms:

• 4-Fluoro-3-Aminobenzotrifluoride
• 3-Amino-4-Fluorobenzotrifluoride
• Alpha,Alpha,Alpha,6-Tetrafluoro-M-Toluidine
• 2-Fluoro-5-(Trifluoromethyl)Aniline/3-Amino-4-Fluorobenzotrifluoride
• 4-Fluoro-3-Aminotrifluoromethylbenzene
• 3-Amino-4-fluorobenzotrifluoride, 97% (2-Fluoro-5-(trifluoromethyl)aniline)
• 3-Amino-4-fluorobenzotrifluoride 97%
• 3-Chloro-2,4,5,6-Tetrafluorobenzoic Acid
• 2-Fluoro-5-Trifluoromethyl Aniline

3-Amino-4-fluorobenzotrifluoride

CAS: 535-52-4

Formula: C₇H₅F₄N

Purity: >98.0%(GC)

Color and Shape: White - Yellow Liquid

Molecular weight: 179.12

Ref: 3B-A1582

2-Fluoro-5-(trifluoromethyl)aniline, 97%

CAS: 535-52-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₅F₄N

Purity: 97%

Color and Shape: Clear yellow, Liquid

Molecular weight: 179.12

Ref: 02-A17556

3-Amino-4-fluorobenzotrifluoride

CAS: 535-52-4

Formula: C₇H₅F₄N

Purity: 97%

Color and Shape: Liquid

Molecular weight: 179.118

Ref: 10-F003129

2-Fluoro-5-(trifluoromethyl)aniline

CAS: 535-52-4

Formula: C₇H₅F₄N

Purity: 95%

Color and Shape: Liquid

Molecular weight: 179.1149

Ref: IN-DA003H9X

3-Amino-4-fluorobenzotrifluoride

CAS: 535-52-4

3-Amino-4-fluorobenzotrifluoride

Formula: C₇H₅F₄N

Purity: 97%

Color and Shape: clear. faint green/light yellow liquid

Molecular weight: 179.11g/mol

Ref: 54-PC1074

2-Fluoro-5-(trifluoromethyl)aniline

Controlled Product

CAS: 535-52-4

Applications 2-Fluoro-5-(trifluoromethyl)aniline has been used as a reactant for the synthesis of 5,6,7-trimethoxy-N-phenyl(ethyl)-4-aminoquinazoline derivatives with anticancer activities.
References Zhang, Y., et. al.: Eur. J. Med. Chem., 66, 335 (2013)

Formula: C₇H₅F₄N

Color and Shape: Neat

Molecular weight: 179.11

Ref: TR-F596095