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CAS 53515-91-6

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Haloperidol lactate

Description:
Haloperidol lactate is a derivative of haloperidol, an antipsychotic medication primarily used to treat schizophrenia and acute psychosis. It is characterized by its lactate salt form, which enhances its solubility and bioavailability when administered. Haloperidol lactate is typically presented as a white to off-white crystalline powder, and it is soluble in water, making it suitable for injection. The compound acts primarily as a dopamine antagonist, particularly at the D2 receptor, which contributes to its therapeutic effects in managing psychotic disorders. Its pharmacokinetics involve a relatively long half-life, allowing for sustained therapeutic action. Common side effects may include sedation, extrapyramidal symptoms, and potential cardiovascular effects. Due to its potency, careful dosing and monitoring are essential to minimize adverse reactions. Haloperidol lactate is often utilized in acute settings, such as emergency psychiatry, due to its rapid onset of action. As with all medications, it should be used under the guidance of a healthcare professional, considering individual patient factors and potential drug interactions.
Formula:C21H23ClFNO2·C3H6O3
InChI:InChI=1S/C21H23ClFNO2.C3H6O3/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16;1-2(4)3(5)6/h3-10,26H,1-2,11-15H2;2,4H,1H3,(H,5,6)
InChI key:InChIKey=BVUSNQJCSYDJJG-UHFFFAOYSA-N
SMILES:OC1(C2=CC=C(Cl)C=C2)CCN(CCCC(=O)C3=CC=C(F)C=C3)CC1.C(C(O)=O)(C)O
Synonyms:
  • 1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-, 2-hydroxypropanoate (salt)
  • Haloperidol lactate
  • Propanoic acid, 2-hydroxy-, compd. with 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone (1:1)
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