CAS 5352-74-9
:(9cis,13cis)-retinoic acid
Description:
(9cis,13cis)-retinoic acid, also known as 9-cis-retinoic acid, is a derivative of vitamin A and plays a crucial role in various biological processes, particularly in vision and cellular differentiation. This compound is characterized by its two cis double bonds located at the 9th and 13th carbon positions of the carbon chain, which influence its biological activity and interaction with retinoic acid receptors. It is a yellow to orange solid at room temperature and is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but has limited solubility in water. (9cis,13cis)-retinoic acid is known for its role in regulating gene expression and is involved in processes such as embryonic development and skin health. It is also studied for its potential therapeutic applications in treating skin disorders and certain types of cancer. Due to its biological significance, it is essential to handle this compound with care, as it can exhibit teratogenic effects if misused during pregnancy.
Formula:C20H28O2
InChI:InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14-
InChI key:InChIKey=SHGAZHPCJJPHSC-CDMOMSTLSA-N
SMILES:C(=C/C(=C\C=C\C(=C/C(O)=O)\C)/C)\C=1C(C)(C)CCCC1C
Synonyms:- 9,13-Di-cis-retinoic acid
- (9-cis,13-cis)-Retinoic acid
- 9-cis,13-cis-Retinoic acid
- Retinoic acid, 9-cis,13-cis-
- Retinoic acid, (9-cis,13-cis)-
- (2Z,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexenyl)Nona-2,4,6,8-Tetraenoic Acid
- Tretinoin EP Impurity B
- Tretinoin EP Impurity B (9,13-di-cis-Retinoic Acid)
- 9,13-Di-cis-ra
- Isotretinoin Impurity 2
- Isotretinoin Impurity 2（Isotretinoin EP Impurity B）
- 9,13-Di-cis-Retinoic Acid-13C, d3
- Tretinoin Impurity 2（Tretinoin EP Impurity B）
- Isotretinoin EP impurity B
- Tretinoin EP Impurity B（Isotretinoin EP Impurity B）
- 9-cis,13-cis-Retinoic Acid, ~85%
- 9,13-retinoic acid
- Isotretinoin EP Impurity B（Tretinoin EP Impurity B）
- See more synonyms
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Found 8 products.
9,13-Di-cis-retinoic Acid
CAS:Formula:C20H28O2Purity:95%Color and Shape:SolidMolecular weight:300.4351Tretinoin EP Impurity B (9,13-di-cis-Retinoic Acid)
CAS:Formula:C20H28O2Color and Shape:Yellow SolidMolecular weight:300.449-cis,13-cis-Retinoic Acid, ~85%
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An endogenous retinoid that induces liver fibrosis via the activation of latent transforming growth factor-β. A major plasma metabolite of 9-cis Retinoic Acid (R245000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Okuno, M. et al.: Kanxo, 39, 224 (1998); Nagase, S.: Gidu Gaig. Igak. Kiyo, 47, 25 (1999); Tzimas, G. et al.: Drug Metab. Disp., 22, 928 (1994); Horst, R.L. et al.: Biochemistry, 34, 1203 (1995);<br></p>Formula:C20H28O2Purity:~85%Color and Shape:Light Yellow To Dark BrownMolecular weight:300.44(2Z,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid
CAS:Controlled Product<p>2,4-Dienoylglycerol (2,4-DG) is a metabolite of arachidonic acid and is a potent activator of protein kinase C. It has been shown that 2,4-DG binds to the liver cell membrane and causes a cytoskeletal reorganization. This is an analytical method for measuring the binding constants between 2,4-DG and various proteins in human liver cells. The redox potentials of 2,4-DG are -0.17 V in the pH range of 7 to 8 and -0.12 V in the pH range of 4 to 5. This means that 2,4-DG will be reduced by NADH at pH 7 to 8 and oxidized by NADH at pH 4 to 5. The growth factor activity of 2,4-DG has been demonstrated using human liver cells as well as other cell types such as viruses and cancer cells. The ability of</p>Formula:C20H28O2Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:300.44 g/mol
