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CAS 5355-48-6

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Card-20(22)-enolide, 3-[(O-4-O-acetyl-2,6-dideoxy-β-d-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-d-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-d-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-

Description:
Card-20(22)-enolide, with the CAS number 5355-48-6, is a complex organic compound belonging to the class of cardenolides, which are steroidal glycosides. This substance features a steroid backbone with multiple hydroxyl groups, specifically at the 12 and 14 positions, contributing to its biological activity. The presence of a unique glycosidic structure, consisting of three dideoxy-β-D-ribo-hexopyranosyl units linked through (1→4) bonds, enhances its solubility and potential interactions with biological systems. The acetyl group at the 4-position of the first sugar unit further modifies its properties, potentially influencing its pharmacokinetics and bioactivity. Cardenolides are known for their effects on cardiac function, often used in medicinal applications, particularly in treating heart conditions. The specific stereochemistry indicated by the (3β,5β,12β) configuration is crucial for its biological activity, as it determines the compound's interaction with cellular targets. Overall, Card-20(22)-enolide exemplifies the intricate relationship between structure and function in bioactive natural products.
Formula:C43H66O15
InChI:InChI=1/C43H66O15/c1-20-38(55-23(4)44)30(45)17-36(53-20)57-40-22(3)54-37(18-32(40)47)58-39-21(2)52-35(16-31(39)46)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(48)42(6)27(10-12-43(28,42)50)24-13-34(49)51-19-24/h13,20-22,25-33,35-40,45-48,50H,7-12,14-19H2,1-6H3
InChI key:InChIKey=NREAGDHHMSOWKZ-DXJNJSHLSA-N
SMILES:O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5C[C@H](O)[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](OC(C)=O)[C@@H](C)O7)[C@@H](C)O6)[C@@H](C)O5)CC4)[H])(C[C@@H](O)[C@]1(C)[C@H](CC2)C=8COC(=O)C8)[H])[H]
Synonyms:
  • (3β,5β,12β)-3-[(O-4-O-Acetyl-2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
  • 16'-Acetyldigoxin
  • 3-{[4-O-acetyl-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
  • 4'''-Acetyldigoxin
  • Acetyl-digoxin-beta
  • Card-20(22)-enolide, 3-((O-4-O-acetyl-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1.4)-O-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1.4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
  • Card-20(22)-enolide, 3-[(O-4-O-acetyl-2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
  • Cardioreg
  • Cor-Puren
  • Digorid B
  • See more synonyms
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Found 7 products.
  • CymitQuimica logo
    EDQM - European Pharmacopoeia
    + Info

    β-ACETYLDIGOXIN FOR PEAK IDENTIFICATION CRS

    CAS:
    <p>β-ACETYLDIGOXIN FOR PEAK IDENTIFICATION CRS</p>
    Formula:C43H66O15
    Molecular weight:822.9751

    Ref: 41-Y0000642

    10mg
    115.00€
  • β-ACETYLDIGOXIN CRS
    EDQM - European Pharmacopoeia
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    β-ACETYLDIGOXIN CRS

    CAS:
    <p>β-ACETYLDIGOXIN CRS</p>
    Formula:C43H66O15
    Color and Shape:White.
    Molecular weight:822.9751

    Ref: 41-Y0000565

    50mg
    115.00€
  • b-Acetyl digoxin
    Glentham
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    b-Acetyl digoxin

    CAS:
    Formula:C43H66O15
    Purity:≥ 98.0%
    Color and Shape:White solid
    Molecular weight:822.98

    Ref: 7W-GC5455

    ne
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  • Digoxin EP Impurity J
    TLC
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    Digoxin EP Impurity J

    CAS:
    Formula:C43H66O15
    Molecular weight:823.00

    Ref: 4Z-D-759

    5mg
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  • β-Acetyl Digoxin
    TRC
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    β-Acetyl Digoxin

    Controlled Product
    CAS:
    <p>Applications Digoxin derivative, a cardiotonic glycosides steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 ( 2000), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Wang, J., et al.: Anal. Chim. Acta, 601, 156 (2007),<br></p>
    Formula:C43H66O15
    Color and Shape:Neat
    Molecular weight:822.98

    Ref: TR-A173665

    1mg
    354.00€
    5mg
    1,551.00€
    10mg
    2,662.00€
  • β-Acetyldigoxin
    Biosynth
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    β-Acetyldigoxin

    CAS:
    <p>β-Acetyldigoxin is a cardiac glycoside, which is a naturally derived chemical compound primarily sourced from Digitalis lanata, a species of the foxglove plant. These compounds exert their effects by inhibiting the Na+/K+-ATPase enzyme, leading to an increase in intracellular calcium concentrations. This mechanism enhances myocardial contractility, contributing to its positive inotropic effects, which are essential in treating heart-related ailments.</p>
    Formula:C43H66O15
    Purity:Min. 95%
    Molecular weight:822.98 g/mol

    Ref: 3D-OA164421

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  • Digoxin EP Impurity J
    Standalix
    + Info

    Digoxin EP Impurity J

    CAS:
    Formula:C43H66O15
    Molecular weight:823

    Ref: ST-EA-CP-D1200009

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