CAS 53553-14-3

methyl 2-chloro-3-nitrobenzoate

Description:

Methyl 2-chloro-3-nitrobenzoate, with the CAS number 53553-14-3, is an organic compound that belongs to the class of benzoate esters. It features a benzoate structure where a methyl group is esterified to the carboxylic acid moiety of benzoic acid, and it is substituted with both a chlorine atom and a nitro group on the aromatic ring. The presence of these substituents contributes to its chemical reactivity and physical properties. Typically, this compound appears as a yellow to brown solid or liquid, depending on its purity and specific conditions. It is generally soluble in organic solvents but has limited solubility in water due to its hydrophobic aromatic structure. Methyl 2-chloro-3-nitrobenzoate can be used in various chemical syntheses, particularly in the production of pharmaceuticals and agrochemicals, owing to its electrophilic nature. Safety precautions should be taken when handling this compound, as it may pose health risks through inhalation or skin contact.

Formula: C₈H₆ClNO₄

InChI: InChI=1/C8H6ClNO4/c1-14-8(11)5-3-2-4-6(7(5)9)10(12)13/h2-4H,1H3

SMILES: COC(=O)c1cccc(c1Cl)N(=O)=O

Synonyms:

• Benzoic Acid, 2-Chloro-3-Nitro-, Methyl Ester

METHYL 2-CHLORO-3-NITROBENZOATE

CAS: 53553-14-3

Formula: C₈H₆ClNO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 215.5905

Ref: IN-DA00D8OT

Methyl 2-chloro-3-nitrobenzoate

CAS: 53553-14-3

Methyl 2-chloro-3-nitrobenzoate

Purity: 99%

Molecular weight: 215.59g/mol

Ref: 54-OR310899

2-Chloro-3-nitrobenzoic acid methyl ester

CAS: 53553-14-3

2-Chloro-3-nitrobenzoic acid methyl ester is a chemical compound that has been shown to inhibit the activity of serotonin. The compound binds to the 5-HT3 receptor on the enteric neurons and inhibits the release of serotonin in the bowel, which is one of the two major sites of action for this drug. This inhibition leads to reduced motility and decreased secretion in the bowel, which helps relieve symptoms in patients with irritable bowel syndrome (IBS). It has also been shown that 2-chloro-3-nitrobenzoic acid methyl ester is able to inhibit the production of serotonin from tryptophan by inhibiting an enzyme called aromatic amino acid decarboxylase.
2-Chloro-3-nitrobenzoic acid methyl ester has a high affinity for both rat and human 5ht3 receptors. The kinetics and thermodynamics of this reaction have been studied using methanol as a

Formula: C₈H₆ClNO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 215.59 g/mol

Ref: 3D-FC55358

Methyl 2-chloro-3-nitrobenzoate

CAS: 53553-14-3

Formula: C₈H₆ClNO₄

Purity: 97%

Molecular weight: 215.59

Ref: 10-F338167