CAS 53587-29-4

L-Dopa-2,5,6-d3 [3-(3,4-dihydroxyphenyl-2,5,6-d3)-L-alanine]

Description:

L-Dopa-2,5,6-d3, also known as 3-(3,4-dihydroxyphenyl-2,5,6-d3)-L-alanine, is a deuterated form of L-Dopa, an amino acid that serves as a precursor to neurotransmitters such as dopamine. This compound is characterized by the presence of deuterium isotopes at specific positions on the carbon backbone, which can be useful in research applications, particularly in metabolic studies and tracing experiments. L-Dopa is primarily utilized in the treatment of Parkinson's disease and is known for its ability to cross the blood-brain barrier, where it is converted to dopamine. The deuterated version may exhibit altered pharmacokinetics or metabolic pathways compared to its non-deuterated counterpart, making it valuable for scientific investigations. In terms of physical properties, L-Dopa-2,5,6-d3 is typically a white to off-white crystalline powder, soluble in water, and has a specific melting point range. Its chemical structure includes hydroxyl groups that contribute to its reactivity and biological activity.

Formula: C₉H₈D₃NO₄

InChI: InChI=1/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1/i1D,2D,4D

SMILES: c1(c(c(c(c(c1C[C@@H](C(=O)O)N)[2H])O)O)[2H])[2H]

Synonyms:

• L-DOPA-ring-d3
• 3-hydroxy-L-(2,5,6-~2~H_3_)tyrosine

L-DOPA-2,5,6-D3

CAS: 53587-29-4

L-DOPA-2,5,6-D3

Purity: 98%

Molecular weight: 200.21g/mol

Ref: 54-DE2102

Levodopa-d3

CAS: 53587-29-4

Formula: C₉H₈D₃NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 200.21

Ref: 4Z-D-323

L-Dopa-2,5,6-d3

CAS: 53587-29-4

Formula: (HO)₂C₆D₃CH₂CH(NH₂)COOH

Purity: 98 atom % D

Color and Shape: White To Brown Solid

Molecular weight: 200.08764

Ref: 3U-D1570

L-DOPA-2,5,6-d3

Controlled Product

CAS: 53587-29-4

Formula: C₉₂H₃H₈NO₄

Ref: TR-TRC-D533752

L-DOPA-2,5,6-d3

Controlled Product

CAS: 53587-29-4

Stability Light Sensitive
Applications Natural isomer of the immediate precursor of dopamine; product of tyrsine hydroxylase.
References Tabar, et al.: Pharmacol. Biochem. Behav., 33, 139 (1989), De Souza Silva, et al.: J. Neurochem., 68, 233 (1997), Feigin, A., et al.: Neurology, 57, 2083 (2001),

Formula: C₉₂H₃H₈NO₄

Color and Shape: Neat

Molecular weight: 200.21

Ref: TR-D533752

3-(3,4-DIHYDROXYPHENYL-2,5,6-D3)-L-ALANINE

CAS: 53587-29-4

Formula: C₉H₈D₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 200.2064

Ref: IN-DA00DDQO