CAS 536-33-4

Ethionamide

Description:

Ethionamide, with the CAS number 536-33-4, is a synthetic organic compound primarily used as an antibiotic in the treatment of tuberculosis. It belongs to the class of thioamide compounds and is characterized by its thioamide functional group, which contributes to its biological activity. Ethionamide is typically presented as a white to off-white crystalline powder that is soluble in water and organic solvents. Its mechanism of action involves inhibiting the synthesis of mycolic acids, essential components of the mycobacterial cell wall, thereby exerting its bactericidal effects against Mycobacterium tuberculosis. Ethionamide is often used in combination with other antitubercular agents to enhance efficacy and reduce the risk of resistance. While it is effective, it can also cause side effects, including gastrointestinal disturbances and potential hepatotoxicity, necessitating careful monitoring during treatment. Overall, ethionamide plays a crucial role in the management of drug-resistant tuberculosis, highlighting its importance in public health.

Formula: C₈H₁₀N₂S

InChI: InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)

InChI key: InChIKey=AEOCXXJPGCBFJA-UHFFFAOYSA-N

SMILES: C(N)(=S)C=1C=C(CC)N=CC1

Synonyms:

• 1314Th
• 2-(Ethylsulfanyl)Pyridine-4-Carboxamide
• 2-Ethyl-4-pyridinecarbothioamide
• 2-Ethyl-4-thiocarbamoylpyridine
• 2-Ethyl-thioisonicotinamide
• 2-Ethylisonicotinethioamide
• 2-Ethylisonicotinic acid thioamide
• 2-Ethylisonicotinothioamide
• 2-Ethylisothionicotinamide
• 2-Ethylpyridine-4-Carbothioamide
• 2-Ethylpyridine-4-thiocarboxamide
• 2-Ethylthioisonicotinamide
• 4-Pyridinecarbothioamide, 2-ethyl-
• Amidazine
• Bayer 5312
• Ethina
• Ethinamide
• Ethionamid
• Ethioniamide
• Ethylisothiamide
• Ethyonomide
• Etimid
• Etionamid
• Etionamida
• Etioniamid
• Etionid
• Etionizin
• Etionizine
• F.I. 58-30
• Iridocin
• Iridocin Bayer
• Iridozin
• Isonicotinamide, 2-ethylthio-
• Isonicotinimidic acid, 2-ethylthio-
• Nizotin
• Nsc 255115
• Sertinon
• Teberus
• Thianid
• Thianide
• Thioamide
• Thiodine
• Tianid
• Tiomid
• Trecator
• Trecator SC
• Trekator
• Trescatyl
• α-Ethylisothionicotinamide

Ethionamide

CAS: 536-33-4

Formula: C₈H₁₀N₂S

Purity: >98.0%(T)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 166.24

Ref: 3B-E0695

Ethionamide, 98%

CAS: 536-33-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₀N₂S

Purity: 98%

Color and Shape: Yellow, Powder or crystals or crystalline powder

Molecular weight: 166.24

Ref: 02-J66582

ETHIONAMIDE FOR SYSTEM SUITABILITY CRS

CAS: 536-33-4

ETHIONAMIDE FOR SYSTEM SUITABILITY CRS

Formula: C₈H₁₀N₂S

Color and Shape: Crystalline Powder. Yellow. Crystals. Powder.

Molecular weight: 166.2434

Ref: 41-Y0001686

ETHIONAMIDE CRS

CAS: 536-33-4

ETHIONAMIDE CRS

Formula: C₈H₁₀N₂S

Color and Shape: Crystalline Powder. Yellow. Crystals. Powder.

Molecular weight: 166.2434

Ref: 41-E2000000

Ethionamide

CAS: 536-33-4

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₈H₁₀N₂S

Color and Shape: Yellow Powder

Molecular weight: 166.05647

Ref: 45-1261004

Ethionamide

CAS: 536-33-4

Ethionamide: antibacterial used to treat TB; may block mycolic acid synthesis, disrupting bacterial walls. Its effect varies with concentration and organism.

Formula: C₈H₁₀N₂S

Purity: 99.45% - 99.92%

Color and Shape: Yellow Crystals From Ethanol Odor (Ntp 1992)

Molecular weight: 166.24

Ref: TM-T1165

4-Pyridinecarbothioamide, 2-ethyl-

CAS: 536-33-4

Formula: C₈H₁₀N₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.2434

Ref: IN-DA00I9K8

Ethionamide

CAS: 536-33-4

Ethionamide

Purity: ≥98%

Molecular weight: 166.24g/mol

Ref: 54-BUP17752

2-Ethylpyridine-4-Carbothioamide

CAS: 536-33-4

2-Ethylpyridine-4-Carbothioamide

Purity: 98%

Molecular weight: 166.24g/mol

Ref: 54-OR1010448

Ethionamide

CAS: 536-33-4

Formula: C₈H₁₀N₂S

Molecular weight: 166.24

Ref: 4Z-E-371

Ethionamide

Controlled Product

CAS: 536-33-4

Formula: C₈H₁₀N₂S

Color and Shape: Neat

Molecular weight: 166.24

Ref: 86-MM0845.00

Ethionamide

CAS: 536-33-4

Formula: C₈H₁₀N₂S

Purity: 98.0 - 102.0 % (anhydrous basis)

Color and Shape: Yellow crystalline powder

Molecular weight: 166.24

Ref: 7W-GA6196

Ethionamide-d3

Controlled Product

CAS: 536-33-4

Applications Ethionamide-d3 is the isotope labelled analogue of Ethionamide (E890420), a antibacterial (tuberculostatic) agent.
References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),

Formula: C₈H₇D₃N₂S

Color and Shape: Neat

Molecular weight: 169.26

Ref: TR-E890422

Ethionamide

CAS: 536-33-4

Applications Antibacterial (tuberculostatic).
References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),

Formula: C₈H₁₀N₂S

Color and Shape: Neat

Molecular weight: 166.24

Ref: TR-E890420

2-Ethyl-thioisonicotinamide

CAS: 536-33-4

Formula: C₈H₁₀N₂S

Purity: 96%

Color and Shape: Solid

Molecular weight: 166.24

Ref: 10-F023863

Ethionamide

CAS: 536-33-4

Color and Shape: Neat

Ref: 61-FOR0845.00