CAS 53648-05-8

Ibuproxam

Description:

Ibuproxam, with the CAS number 53648-05-8, is a non-steroidal anti-inflammatory drug (NSAID) that exhibits analgesic and antipyretic properties. It is primarily used for the relief of pain and inflammation. The compound is characterized by its ability to inhibit cyclooxygenase enzymes (COX-1 and COX-2), which play a crucial role in the synthesis of prostaglandins, mediators of pain and inflammation. Ibuproxam is typically administered orally and is known for its relatively rapid onset of action. Its chemical structure includes a propionic acid derivative, which is common among NSAIDs, contributing to its efficacy in reducing fever and alleviating mild to moderate pain. The drug is generally well-tolerated, but like other NSAIDs, it may have side effects such as gastrointestinal discomfort, cardiovascular risks, and potential renal impairment, especially with prolonged use. As with any medication, it is important to use ibuproxam under medical supervision to ensure safety and effectiveness.

Formula: C₁₃H₁₉NO₂

InChI: InChI=1/C13H19NO2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(15)14-16/h4-7,9-10,16H,8H2,1-3H3,(H,14,15)

InChI key: InChIKey=BYPIURIATSUHDW-UHFFFAOYSA-N

SMILES: C(C(NO)=O)(C)C1=CC=C(CC(C)C)C=C1

Synonyms:

• 2-(4-Isobutylphenyl)propionohydroxamic acid
• 2-(4-Isobutylphenyl)propionohydroxamsaeure
• Benzeneacetamide, N-hydroxy-alpha-methyl-4-(2-methylpropyl)-
• Benzeneacetamide, N-hydroxy-α-methyl-4-(2-methylpropyl)-
• Deflogon
• G 277
• Ibudros
• Ibuproxam [INN]
• Ibuproxamum
• Ibuproxamum [INN-Latin]
• N-Hydroxy-2-(4-isobutylphenyl)propionamid
• N-Hydroxy-α-methyl-4-(2-methylpropyl)benzeneacetamide
• N-hydroxy-2-[4-(2-methylpropyl)phenyl]propanamide
• Nsc 305528
• Unii-O3Ld16O96Z
• p-Isobutylhydratropohydroxamic acid
• Ibuproxam
• N-Hydroxy-alpha-methyl-4-(2-methylpropyl)-benzeneacetamide
• N-Hydroxy-α-methyl-4-isobutylbenzeneacetamide

rac Ibuproxam

Controlled Product

CAS: 53648-05-8

Applications rac Ibuproxam is a poorly water-soluble anti-inflammatory drug.
References Cirri, M., et al.: Drug Dev. Ind. Pharm., 30, 65 (2004)

Formula: C₁₃H₁₉NO₂

Color and Shape: Neat

Molecular weight: 221.3

Ref: TR-I140200

Ibuproxam

CAS: 53648-05-8

Ibuproxam, a nonsteroidal antiinflammatory drug (NSAID), is used for the treatment of musculoskeletal pain, arthritis, and soft-tissue disorders.

Formula: C₁₃H₁₉NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 221.3

Ref: TM-T27573

rac Ibuproxam-d3

Controlled Product

CAS: 53648-05-8

Formula: C₁₃D₃H₁₆NO₂

Color and Shape: Neat

Molecular weight: 224.314

Ref: TR-I140202