CAS 53648-55-8

(-)-Dezocine

Description:

(-)-Dezocine is a synthetic opioid analgesic that exhibits both agonist and antagonist properties at opioid receptors, primarily the mu and kappa receptors. It is characterized by its unique chemical structure, which includes a piperidine ring, contributing to its pharmacological effects. As an analgesic, (-)-Dezocine is used in clinical settings for the management of moderate to severe pain, often in postoperative or chronic pain scenarios. Its dual action allows it to provide pain relief while potentially reducing the risk of some side effects commonly associated with pure agonists, such as respiratory depression. The substance has a relatively low potential for abuse compared to other opioids, although caution is still advised due to its opioid nature. Pharmacokinetically, (-)-Dezocine is typically administered via injection, with its effects onset occurring within a short time frame. As with all opioids, monitoring for side effects such as sedation, nausea, and potential dependency is essential during its use.

Formula: C₁₆H₂₃NO

InChI: InChI=1/C16H23NO/c1-16-8-4-2-3-5-12(15(16)17)9-11-6-7-13(18)10-14(11)16/h6-7,10,12,15,18H,2-5,8-9,17H2,1H3/t12-,15+,16+/m1/s1

InChI key: InChIKey=VTMVHDZWSFQSQP-VBNZEHGJSA-N

SMILES: C[C@@]12C=3C(C[C@@]([C@@H]1N)(CCCCC2)[H])=CC=C(O)C3

Synonyms:

• (5R,11S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzo[10]annulen-3-ol
• (5R,11S,13S)-13-Amino-5,6,7,8,9,10,11,12-octahydro-5-methyl-5,11-methanobenzocyclodecen-3-ol
• (5R,11S,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzo[10]annulen-3-ol
• (5S,11R,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzo[10]annulen-3-ol
• 5,11-Methanobenzocyclodecen-3-ol, 13-amino-5,6,7,8,9,10,11,12-octahydro-5-methyl-, (5R,11S,13S)-
• 5,11-Methanobenzocyclodecen-3-ol, 13-amino-5,6,7,8,9,10,11,12-octahydro-5-methyl-, [5R-(5α,11α,13S*)]-
• 53648-55-8
• Wy 16225
• Dezocine

Dezocine

CAS: 53648-55-8

Formula: C₁₆H₂₃NO

Color and Shape: Off-White Solid

Molecular weight: 245.37

Ref: 4Z-D-216001

Dezocine

CAS: 53648-55-8

Formula: C₁₆H₂₃NO

Molecular weight: 245.36

Ref: 7W-GP8135

Dezocine

Controlled Product

CAS: 53648-55-8

Applications Dezocine is an opioid analgesic that is related to Pentazocine (P274300). Dezocine is used to relieve post-operative pain with its potency comparable to Meperidine (M223900).
References Zacny, J.P. et al.: Anesth. Analg., 74, 523 (1992); Camu, F. et al.: Acta Anaesthesiol. Belg., 30, 183 (1979); Oosterlinck, W. et al.: Curr. Med. Res., 6, 474 (1980);

Formula: C₁₆H₂₃NO

Color and Shape: White Solid

Molecular weight: 245.36

Ref: TR-D299800

Dezocine

CAS: 53648-55-8

Formula: C₁₆H₂₃NO

Molecular weight: 245.37

Ref: ST-EA-CP-D293000