CAS 53658-98-3

Prosta-5,13-dien-1-oicacid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)-

Description:

Prosta-5,13-dien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)-, with the CAS number 53658-98-3, is a synthetic compound that belongs to the class of prostaglandins, which are lipid compounds derived from fatty acids. This substance exhibits anti-inflammatory and analgesic properties, making it relevant in pharmacological applications. Its structure features multiple functional groups, including a carboxylic acid, hydroxyl, and ketone, contributing to its biological activity. The specific stereochemistry indicated by the (5Z, 13E, 15R) notation suggests a defined spatial arrangement of atoms, which is crucial for its interaction with biological targets. Prostaglandins like this compound play significant roles in various physiological processes, including the modulation of inflammation, pain, and vascular functions. The compound's stability, solubility, and reactivity can vary based on environmental conditions, influencing its potential therapeutic uses. Overall, this compound represents a complex interaction of chemical properties that are essential for its biological function and therapeutic potential.

Formula: C₂₂H₃₆O₄

Synonyms:

• 11-Deoxy-16,16-dimethyl-PGE2
• 15-Hydroxy-16,16-dimethyl-9-oxoprosta-5,13-dienoic acid
• Ay 24609

11-deoxy-16,16-dimethyl Prostaglandin E2

CAS: 53658-98-3

11-Deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of Prostaglandin E2 (PGE2), acting as an agonist for both EP2 and EP3 receptors. It effectively inhibits gastric acid secretion and ulcer formation in rats, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively. This compound is also 900 times more potent than Prostaglandin F2α (PGF2α) in inducing contraction of human respiratory tract smooth muscle in vitro.

Formula: C₂₂H₃₆O₄

Color and Shape: Solid

Molecular weight: 364.526

Ref: TM-T84585