CAS 536748-46-6

Eribaxaban

Description:

Eribaxaban is an anticoagulant medication that belongs to the class of direct factor Xa inhibitors. It is designed to prevent thrombus formation by selectively inhibiting factor Xa, an essential enzyme in the coagulation cascade. This inhibition disrupts the conversion of prothrombin to thrombin, thereby reducing the formation of fibrin clots. Eribaxaban is characterized by its oral bioavailability, allowing for convenient administration. The substance exhibits a relatively short half-life, which necessitates careful dosing to maintain therapeutic levels. Its pharmacokinetics are influenced by factors such as renal function and hepatic metabolism, making patient-specific considerations important in its use. Eribaxaban is primarily investigated for its potential in treating and preventing venous thromboembolism and other thrombotic disorders. As with other anticoagulants, monitoring for bleeding risks is crucial during treatment. Overall, Eribaxaban represents a significant advancement in anticoagulant therapy, offering a targeted approach to managing coagulation disorders.

Formula: C₂₄H₂₂ClFN₄O₄

InChI: InChI=1S/C24H22ClFN4O4/c1-34-18-13-21(30(14-18)24(33)27-16-7-5-15(25)6-8-16)23(32)28-20-10-9-17(12-19(20)26)29-11-3-2-4-22(29)31/h2-12,18,21H,13-14H2,1H3,(H,27,33)(H,28,32)/t18-,21-/m1/s1

InChI key: InChIKey=QQBKAVAGLMGMHI-WIYYLYMNSA-N

SMILES: C(NC1=C(F)C=C(C=C1)N2C(=O)C=CC=C2)(=O)[C@@H]3N(C(NC4=CC=C(Cl)C=C4)=O)C[C@H](OC)C3

Synonyms:

• (2R,4R)-4-Methoxypyrrolidine-1,2-dicarboxylic acid 1-[(4-chlorophenyl)amide] 2-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)phenyl]amide]
• PD 348292
• Eribaxaban
• 1,2-Pyrrolidinedicarboxamide, N1-(4-chlorophenyl)-N2-[2-fluoro-4-(2-oxo-1(2H)-pyridinyl)phenyl]-4-methoxy-, (2R,4R)-
• (2R,4R)-N1-(4-Chlorophenyl)-N2-[2-fluoro-4-(2-oxo-1(2H)-pyridinyl)phenyl]-4-methoxy-1,2-pyrrolidinedicarboxamide

Eribaxaban

CAS: 536748-46-6

Eribaxaban

Purity: ≥98%

Molecular weight: 484.91g/mol

Ref: 54-BUP11565

Eribaxaban

CAS: 536748-46-6

Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.

Formula: C₂₄H₂₂ClFN₄O₄

Purity: 98.99% - 99.13%

Color and Shape: Solid

Molecular weight: 484.91

Ref: TM-T31668