CAS 536759-91-8

Ethyl 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Description:

Ethyl 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is a complex organic compound characterized by its unique pyrazolo-pyridine structure, which incorporates multiple functional groups, including an ester (ethyl carboxylate), a methoxy group, and a nitro group. This compound typically exhibits a range of chemical properties, including moderate solubility in organic solvents and potential reactivity due to the presence of electrophilic and nucleophilic sites. Its molecular structure suggests potential biological activity, making it of interest in medicinal chemistry, particularly for its possible applications in drug development. The presence of the nitro group may enhance its pharmacological properties, while the methoxy group can influence its lipophilicity and bioavailability. As with many complex organic compounds, careful handling and characterization are essential, as they may exhibit specific stability and reactivity profiles under varying conditions. Overall, this compound represents a significant area of study for researchers exploring novel therapeutic agents.

Formula: C₂₂H₂₀N₄O₆

InChI: InChI=1S/C22H20N4O6/c1-3-32-22(28)19-18-12-13-24(14-4-6-16(7-5-14)26(29)30)21(27)20(18)25(23-19)15-8-10-17(31-2)11-9-15/h4-11H,3,12-13H2,1-2H3

InChI key: InChIKey=RQNAOIQEGPVYTC-UHFFFAOYSA-N

SMILES: O=C1C=2N(N=C(C(OCC)=O)C2CCN1C3=CC=C(N(=O)=O)C=C3)C4=CC=C(OC)C=C4

Synonyms:

• 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-, ethyl ester
• 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl este
• 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
• Ethyl 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Apixaban Related Compound F (Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate)

CAS: 536759-91-8

Lactams, nesoi

Formula: C₂₂H₂₀N₄O₆

Color and Shape: Light Brown Powder

Molecular weight: 436.13828

Ref: 45-1040774

4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

CAS: 536759-91-8

Formula: C₂₂H₂₀N₄O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 436.4174

Ref: IN-DA00DB5X

Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

CAS: 536759-91-8

Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Purity: 98%

Molecular weight: 436.42g/mol

Ref: 54-OR95814

Apixaban USP Related Compound F

CAS: 536759-91-8

Formula: C₂₂H₂₀N₄O₆

Molecular weight: 436.42

Ref: 4Z-A-10258

Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

CAS: 536759-91-8

Purity: 97%

Molecular weight: 436.42401123046875

Ref: 10-F788629

Apixaban Tetrahydro Impurity

CAS: 536759-91-8

Formula: C₂₂H₂₀N₄O₆

Molecular weight: 436.42

Ref: ST-EA-CP-A3024

Ethyl 1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Controlled Product

CAS: 536759-91-8

Applications Ethyl 1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an intermediate in the synthesis of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation
References Pinto, D.J.P., et. al.: J. Med. Chem., 50, 5339 (2007); Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011)

Formula: C₂₂H₂₀N₄O₆

Color and Shape: Neat

Molecular weight: 436.417

Ref: TR-E679570

4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo [3,4-c]pyridine-3-carboxylic acid ethyl ester

CAS: 536759-91-8

Please enquire for more information about 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo [3,4-c]pyridine-3-carboxylic acid ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₂H₂₀N₄O₆

Purity: Min. 95%

Molecular weight: 436.42 g/mol

Ref: 3D-LWA75991