CAS 53684-49-4

Bufetolol

Description:

Bufetolol is a beta-adrenergic antagonist, commonly known as a beta-blocker, primarily used in the treatment of hypertension and certain heart conditions. It functions by blocking the action of catecholamines, such as adrenaline, on beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. Bufetolol exhibits selectivity for beta-1 adrenergic receptors, which are predominantly found in the heart, making it effective in reducing cardiac workload and oxygen demand. The compound is characterized by its relatively high lipophilicity, which influences its absorption and distribution in the body. Additionally, bufetolol may have some intrinsic sympathomimetic activity, allowing it to provide a balanced effect on heart rate and contractility. Its pharmacokinetics include oral bioavailability and a moderate half-life, necessitating careful dosing to maintain therapeutic levels. As with other beta-blockers, potential side effects may include fatigue, dizziness, and bradycardia, and it should be used with caution in patients with respiratory conditions or certain cardiovascular diseases.

Formula: C₁₈H₂₉NO₄

InChI: InChI=1S/C18H29NO4/c1-18(2,3)19-11-14(20)12-22-16-8-4-5-9-17(16)23-13-15-7-6-10-21-15/h4-5,8-9,14-15,19-20H,6-7,10-13H2,1-3H3

InChI key: InChIKey=AKLNLVOZXMQGSI-UHFFFAOYSA-N

SMILES: O(CC1CCCO1)C2=C(OCC(CNC(C)(C)C)O)C=CC=C2

Synonyms:

• 1-(Tert-Butylamino)-3-[2-(Tetrahydrofuran-2-Ylmethoxy)Phenoxy]Propan-2-Ol
• 1-(tert-Butylamino)-3-(o-((tetrahydrofurfuryl)oxy)phenoxy)-2-propanol
• 1-[(1,1-Dimethylethyl)amino]-3-[2-[(tetrahydro-2-furanyl)methoxy]phenoxy]-2-propanol
• 2-Propanol, 1-(1,1-(dimethylethyl)amino)-3-(2-((tetrahydro-2-furanyl)methoxy)phenoxy)-
• Bufetolol [INN]
• Bufetololum
• Bufetololum [INN-Latin]
• Unii-Ws1467Rt9Z
• Bufetolol

Bufetolol

Controlled Product

CAS: 53684-49-4

Formula: C₁₈H₂₉NO₄

Color and Shape: Neat

Molecular weight: 323.427

Ref: TR-B689435

1-tert-Butylamino-3-(o-(tetrahydrofurfuryloxy)phenoxy)-2-propanol

CAS: 53684-49-4

1-tert-Butylamino-3-(o-(tetrahydrofurfuryloxy)phenoxy)-2-propanol is a small molecule that is used as a research tool for studying protein interactions. This ligand binds to receptor sites on ion channels and modulates their activity, which may be useful in the pharmacology of various diseases such as asthma, hypertension, and cancer. 1-tert-Butylamino-3-(o-(tetrahydrofurfuryloxy)phenoxy)-2-propanol can also be used to block the binding of antibodies to cells or receptors. It has been shown that this drug inhibits the function of cell migration and invasion by downregulating the expression of proteins such as uPA and MMPs.

Formula: C₁₈H₂₉NO₄

Purity: Min. 95%

Molecular weight: 323.4 g/mol

Ref: 3D-DCA68449

Bufetolol

CAS: 53684-49-4

Bufetolol is an antagonist of beta-adrenoceptor.

Formula: C₁₈H₂₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.43

Ref: TM-T23836