CAS 537-26-8

Tropacocaine

Description:

Tropacocaine, with the CAS number 537-26-8, is a tropane alkaloid derived from the coca plant. It is structurally related to cocaine and exhibits similar pharmacological properties, primarily acting as a local anesthetic. Tropacocaine is characterized by its ability to inhibit the reuptake of neurotransmitters, particularly norepinephrine and dopamine, which contributes to its stimulant effects. The compound is typically a white crystalline solid and is soluble in organic solvents but has limited solubility in water. Its melting point and specific optical rotation can vary based on purity and environmental conditions. Due to its structural similarity to cocaine, tropacocaine has been studied for its potential therapeutic applications, although it is less commonly used in clinical settings. Safety and toxicity profiles are important considerations, as with many alkaloids, and its use is regulated in many jurisdictions. Overall, tropacocaine represents an interesting compound within the realm of medicinal chemistry, particularly in the context of local anesthetics and psychoactive substances.

Formula: C₁₅H₁₉NO₂

InChI: InChI=1/C15H19NO2/c1-16-12-7-8-13(16)10-14(9-12)18-15(17)11-5-3-2-4-6-11/h2-6,12-14H,7-10H2,1H3/t12-,13+,14-

InChI key: InChIKey=XQJMXPAEFMWDOZ-BTTYYORXNA-N

SMILES: O(C(=O)C1=CC=CC=C1)[C@H]2C[C@]3(N(C)[C@@](C2)(CC3)[H])[H]

Synonyms:

• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl benzoate
• 1-alpha-H,5-alpha-H-Tropan-3-beta-ol, benzoate (ester)
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3β-ol, benzoate (ester)
• 3β-Benzoyloxytropane
• 8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, 3-benzoate, (3-exo)-
• 8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, benzoate (ester), (3-exo)-
• 8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, benzoate (ester), exo-
• 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Benzoate
• Benzilate of pseudotropanol
• Benzoyl-psi-tropeine
• Benzoylpseudotropeine
• Benzoylpseudotropine
• Brn 0084408
• Pseudotropanol benzilate
• Pseudotropine benzoate
• Pseudotropine, benzoate (ester)
• Tropacaine
• Tropacocain
• exo-8-Methyl-8-azabicyclo(3.2.1)-octan-3-ol benzoate
• exo-8-Methyl-8-azabicyclo(3.2.1)octan-3-ol, benzoate (ester)
• o-Benzoyltropine
• psi-Tropine benzoate
• ψ-Tropine benzoate
• 5-21-01-00226 (Beilstein Handbook Reference)
• 1αH,5αH-Tropan-3β-ol, benzoate (ester)

Tropacocaine

CAS: 537-26-8

Formula: C₁₅H₁₉NO₂

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 245.322

Ref: BP-BPC0219

Tropacocaine

CAS: 537-26-8

Tropacocaine is a chemical compound classified as a synthetic tropane derivative, which is structurally related to cocaine. It is derived from the coca plant, specifically through synthetic modifications to create a compound with distinct properties. The mode of action of tropacocaine involves its function as a local anesthetic. It blocks sodium channels on nerve membranes, preventing sodium ion influx, which is essential for the generation and conduction of nerve impulses. This blockade leads to a reversible loss of sensation in the targeted area.

Formula: C₁₅H₁₉NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 245.32 g/mol

Ref: 3D-AAA53726