CAS 537-29-1

Norhyoscyamine

Description:

Norhyoscyamine, with the CAS number 537-29-1, is a tropane alkaloid that is structurally related to hyoscyamine and atropine. It is primarily found in plants of the Solanaceae family, particularly in species such as belladonna and henbane. This compound exhibits anticholinergic properties, meaning it can inhibit the action of the neurotransmitter acetylcholine at muscarinic receptors, leading to effects such as pupil dilation, increased heart rate, and reduced secretions. Norhyoscyamine is often studied for its potential therapeutic applications, particularly in treating conditions like motion sickness and muscle spasms. The substance is typically a white to off-white crystalline powder and is soluble in water and alcohol. Its pharmacological effects can vary based on dosage and individual response, and it is important to handle it with care due to its potency and potential toxicity. As with many alkaloids, its use is regulated in many countries due to safety concerns.

Formula: C₁₆H₂₁NO₃

InChI: InChI=1S/C16H21NO3/c18-10-15(11-4-2-1-3-5-11)16(19)20-14-8-12-6-7-13(9-14)17-12/h1-5,12-15,17-18H,6-10H2/t12-,13+,14+,15-/m1/s1

InChI key: InChIKey=ATKYNAZQGVYHIB-CBBWQLFWSA-N

SMILES: O(C([C@H](CO)C1=CC=CC=C1)=O)[C@H]2C[C@@]3(N[C@](C2)(CC3)[H])[H]

Synonyms:

• 1-Tropic acid 3α-nortropanyl ester
• Norhyoscyamine
• Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-
• Tropic acid, 3α-nortropanyl ester

HYOSCYAMINE IMPURITY E CRS

CAS: 537-29-1

HYOSCYAMINE IMPURITY E CRS

Ref: 41-Y0000449

Hyoscyamine EP Impurity E (Norhyoscyamine)

CAS: 537-29-1

Formula: C₁₆H₂₁NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 275.35

Ref: 4Z-A-151011

Norhyoscyamine Hydrochloride

Controlled Product

CAS: 537-29-1

Applications Norhycosamine Hydrochloride is a metabolite of Hycosamine (H674300), a natural compound that has inhibitory activity against cholinesterases.
References Brunhofer, G. et al.: Bioorg. Med. Chem., 20, 6669 (2012); El-Dougdoug, K. et al.: J. App. Sci. Res., 558 (2007);

Formula: C₁₆H₂₁NO₃·ClH

Color and Shape: Neat

Molecular weight: 311.804

Ref: TR-N705650

Hyoscyamine related compound A

CAS: 537-29-1

Hyoscyamine related compound A is a pure, synthetic chemical compound that is used as an impurity standard and can be custom synthesized to meet the requirements of a customer's research and development. Hyoscyamine related compound A is also known as a metabolite in the body, which means it is created from another substance. It is created from the breakdown of Hyoscyamine, which is found in plants such as jimson weed, mandrake, and henbane. Hyoscyamine related compound A has a CAS number of 537-29-1. It can be used to create drug product or pharmacopoeia standards. It has been classified as a custom synthesis by the FDA because it has not been approved for use in humans or animals.

Formula: C₁₆H₂₁NO₃

Purity: Min. 95%

Molecular weight: 275.35 g/mol

Ref: 3D-IH181667

Hyoscyamine EP Impurity E

CAS: 537-29-1

Formula: C₁₆H₂₁NO₃

Molecular weight: 275.35

Ref: ST-EA-CP-H18004

Norhyoscyamine

CAS: 537-29-1

Formula: C₁₆H₂₁NO₃

Molecular weight: 275.35

Ref: ST-EA-CP-H18001