CAS 537-49-5

N-Methyl-L-tyrosine

Description:

N-Methyl-L-tyrosine, also known as 3-methyltyrosine, is an amino acid derivative characterized by the presence of a methyl group attached to the nitrogen atom of the amino group in L-tyrosine. Its chemical formula is C10H13NO3, and it features a phenolic hydroxyl group, which contributes to its solubility in water and its role in biological systems. This compound is often utilized in biochemical research, particularly in studies related to neurotransmitter synthesis, as it acts as an inhibitor of tyrosine hydroxylase, an enzyme critical for the production of catecholamines. N-Methyl-L-tyrosine is also of interest in pharmacology and neurobiology due to its potential effects on dopamine and norepinephrine levels. In terms of physical properties, it typically appears as a white to off-white crystalline powder. Its stability and reactivity are influenced by environmental conditions, such as pH and temperature. As with many amino acid derivatives, it is important to handle N-Methyl-L-tyrosine with care, following appropriate safety protocols in laboratory settings.

Formula: C₁₀H₁₃NO₃

InChI: InChI=1/C10H13NO3/c1-11-9(10(13)14)6-7-2-4-8(12)5-3-7/h2-5,9,11-12H,6H2,1H3,(H,13,14)/t9-/m0/s1

InChI key: InChIKey=AXDLCFOOGCNDST-VIFPVBQESA-N

SMILES: C([C@@H](C(O)=O)NC)C1=CC=C(O)C=C1

Synonyms:

• (+)-N-Methyltyrosine
• (2S)-3-(4-Hydroxyphenyl)-2-(methylamino)propanoic acid
• (2S)-3-(4-Hydroxyphenyl)-2-(methylazaniumyl)propanoate
• <span class="text-smallcaps">L</span>-(+)-N-Methyltyrosine
• <span class="text-smallcaps">L</span>-Tyrosine, N-methyl-
• Andirine
• Andrine
• N-Methyl-<span class="text-smallcaps">L</span>-tyrosine
• N-Methyl-L-tyrosine
• Ratanhin
• Ratanhine
• Surinamin
• Surinamine
• Tyr(AC)
• Tyrosine, N-methyl-, <span class="text-smallcaps">L</span>-
• Tyrosine, N-methyl-, L-
• L-Tyrosine, N-methyl-
• (S)-3-(4-hydroxyphenyl)-2-(MethylaMino)propanoic acid
• -2-(methylamino)
• N-ME-TYR-OH HCL
• N-Methyl-L-tyrosine HCl
• N-ME-TYR-OH USP/EP/BP
• N-ME-TYR-OH
• H-METYR-OH
• N-ALPHA-METHYL-L-TYROSINE HYDROCHLORIDE
• H-L-METYR-OH HCL
• -3-(4-Hydroxyphenyl)
• N-ME-TYROSINE
• N-Me-L-Tyr-OH
• L-Ratanhine
• N-Methyl-L-tyrosine≥ 95% (HPLC)
• N-METHYL-L-TYROSINE HYDROCHLORIDE
• (S)-3-(4-Hydroxyphenyl)-2-(methylamino)propionic acid
• L-Surinamine

N-Me-Tyr-OH

CAS: 537-49-5

Bachem ID: 4011845.

Formula: C₁₀H₁₃NO₃

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 195.22

Ref: 01-4011845

N-Me-Tyr-OH

CAS: 537-49-5

Formula: C₁₀H₁₃NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 195.2151

Ref: IN-DA003T7W

N-Methyl-L-tyrosine

CAS: 537-49-5

Molecular weight: 195.22

Ref: 7W-GM2341

N-Methyl-L-tyrosine - Combretum collinum

CAS: 537-49-5

N-Methyl-L-tyrosine is a molecule that has been studied as a potential treatment for Parkinson's disease. It is chemically related to the amino acid tyrosine and also shares some of its biological properties. N-Methyl-L-tyrosine inhibits the uptake of dopamine by dopamine transporters in cells, which reduces the symptoms of Parkinson's disease. The alkynyl group present in this molecule helps to improve the drug's binding affinity with proctolin, which is a substrate for proton pump inhibitors, and can be used to treat gastrointestinal problems. The clinical use of N-Methyl-L-tyrosine is limited due to its low oral bioavailability; however, it may be effective when administered intravenously or intramuscularly.

Formula: C₁₀H₁₃NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 195.22 g/mol

Ref: 3D-FM25868

N-Methyl-L-tyrosine

CAS: 537-49-5

Formula: C₁₀H₁₃NO₃

Purity: 95%+

Color and Shape: Lumps,Powder

Molecular weight: 195.218

Ref: 10-F223159

N-Methyl-L-tyrosine

Controlled Product

CAS: 537-49-5

Stability Hygroscopic
Applications N-Methyl-L-tyrosine is a tyrosine hydroxylase inhibitor. An antihypertensive in pheochromocytoma. N-Methyl-L-tyrosine from seeds of Combretum zeyheri.
References Itokawa, H., et al.: Phytochemistry, 28, 1667 (1989), Itokawa, H., et al.: Chem. Pharm. Bull., 38, 701 (1990), Silva, R., et al.: J. Pharm. Pharmacol., 53, 535 (2001),

Formula: C₁₀H₁₃NO₃

Color and Shape: Neat

Molecular weight: 195.22

Ref: TR-M332720