CymitQuimica logo

CAS 53714-56-0

:

Leuprorelin

Description:
Leuprorelin, also known as leuprolide, is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH). It is classified as a gonadotropin-releasing hormone agonist and is primarily used in medical applications to treat hormone-sensitive conditions such as prostate cancer, endometriosis, and precocious puberty. Leuprorelin functions by initially stimulating the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a temporary increase in sex hormone levels. However, with continuous administration, it downregulates GnRH receptors, resulting in decreased production of sex hormones. This mechanism is beneficial in managing conditions that are exacerbated by these hormones. Leuprorelin is typically administered via injection and is available in various formulations, including depot forms that allow for extended release. Its chemical structure includes a sequence of amino acids, contributing to its biological activity and specificity. As with any medication, it may have side effects, and its use should be monitored by healthcare professionals.
Formula:C59H84N16O12
InChI:InChI=1/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1
Synonyms:
  • Leuprorelina
  • NSC 377526
  • Leuprolide
  • Leuprolide TFA
  • (D-Leu(sup 6),des-gly-NH2(sup 10),pro-ethylamide(sup 9))-gonadotropin-releasing hormone
  • Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-
  • Eligard
  • A-43818
  • Leuprorelinum [INN-Latin]
  • Leuproreline [INN-French]
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 6 products.