CAS 53714-56-0: Leuprorelin

Description: Leuprorelin, also known as leuprolide, is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH). It is classified as a gonadotropin-releasing hormone agonist and is primarily used in medical applications to treat hormone-sensitive conditions such as prostate cancer, endometriosis, and precocious puberty. Leuprorelin functions by initially stimulating the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a temporary increase in sex hormone levels. However, with continuous administration, it downregulates GnRH receptors, resulting in decreased production of sex hormones. This mechanism is beneficial in managing conditions that are exacerbated by these hormones. Leuprorelin is typically administered via injection and is available in various formulations, including depot forms that allow for extended release. Its chemical structure includes a sequence of amino acids, contributing to its biological activity and specificity. As with any medication, it may have side effects, and its use should be monitored by healthcare professionals.

Formula: C₅₉H₈₄N₁₆O₁₂

InChI: InChI=1/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1

Synonyms:

• Leuprorelina
• NSC 377526
• Leuprolide
• Leuprolide TFA
• (D-Leu(sup 6),des-gly-NH2(sup 10),pro-ethylamide(sup 9))-gonadotropin-releasing hormone
• Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-
• Eligard
• A-43818
• Leuprorelinum [INN-Latin]
• Leuproreline [INN-French]
• (D-Leu(sup 6),des-gly-NH2(sup 10),pro-ethylamide(sup 9))-GNRH
• Luteinizing hormone-releasing hormone (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-
• Leuproreline
• Leuprorelina [INN-Spanish]
• UNII-EFY6W0M8TG
• 5-oxoprolyl-L-histidyl-L-tryptophylseryl-L-tyrosyl-D-valyl-L-valyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide acetate (1:1)
• (D-Leu(sup 6),des-gly-NH2(sup 10),pro-ethylamide(sup 9))-LHRH
• CCRIS 8462
• HSDB 6518
• 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide
• Leuprorelinum

Leuprorelin Acetate

CAS: 53714-56-074381-53-6

• Formula: C₅₉H₈₄N₁₆O₁₂·C₂H₄O₂
• Purity: >97.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 1,269.47

Leuprolide

CAS: 53714-56-0

Highly active luteinizing hormone releasing hormone (LHRH) agonist This Thermo Scientific Chemicals brand product was …

• Formula: C₅₉H₈₄N₁₆O₁₂
• Molecular weight: 1209.41

Leuprorelin CRS

CAS: 53714-56-0

• Formula: C₅₉H₈₄N₁₆O₁₂
• Molecular weight: 1209.398

Leuprorelin

CAS: 53714-56-0

• Formula: C₅₉H₈₄N₁₆O₁₂
• Molecular weight: 1209.41

Leuprorelin (Leuprolide)

CAS: 53714-56-0

• Formula: C₅₉H₈₄N₁₆O₁₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 1209.42

Leuprorelin (Leuprolide)-d10 Trifluoroacetic Acid Salt

CAS: 53714-56-0

• Formula: C₅₉H₇₄D₁₀N₁₆O₁₂·C₂HF₃O₂
• Molecular weight: 1219.48 114.02

Leuprolide-d10 Trifluoroacetic Acid Salt

CAS: 53714-56-0

• Formula: C₅₉H₇₄D₁₀N₁₆O₁₂•x(C₂HF₃O₂)
• Color and Shape: Neat
• Molecular weight: 1219.4611402

Leuprolide

CAS: 53714-56-0

• Formula: C₅₉H₈₄N₁₆O₁₂
• Color and Shape: Off-White
• Molecular weight: 1209.4

[Des-Gly10,Dleu6, ProNHEt9] LH-RH Leuprolide

CAS: 53714-56-0

Please enquire for more information about [Des-Gly10,Dleu6, ProNHEt9] LH-RH Leuprolide including the price, delivery time …

• Formula: C₅₉H₈₄N₆O₁₂
• Purity: Min. 95%
• Molecular weight: 1,069.33 g/mol