CAS 5372-81-6

1,4-Benzenedicarboxylic acid, 2-amino-, 1,4-dimethyl ester

Description:

1,4-Benzenedicarboxylic acid, 2-amino-, 1,4-dimethyl ester, commonly known as dimethyl 2-amino-1,4-benzenedicarboxylate, is an organic compound characterized by its aromatic structure featuring two carboxylate ester groups and an amino group. This compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water due to its hydrophobic aromatic ring. The presence of the amino group imparts basic properties, allowing it to participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. It is often utilized in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. The compound's melting point and boiling point can vary based on purity and environmental conditions. Safety data indicates that it should be handled with care, as it may pose health risks if ingested or inhaled. Proper laboratory practices should be followed when working with this substance to ensure safety and compliance with regulations.

Formula: C₁₀H₁₁NO₄

InChI: InChI=1S/C10H11NO4/c1-14-9(12)6-3-4-7(8(11)5-6)10(13)15-2/h3-5H,11H2,1-2H3

InChI key: InChIKey=DSSKDXUDARIMTR-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C(N)C=C(C(OC)=O)C=C1

Synonyms:

• 1,4-Benzenedicarboxylic acid, 2-amino-, 1,4-dimethyl ester
• 1,4-Benzenedicarboxylic acid, 2-amino-, dimethyl ester
• 1,4-Dimethyl 2-Aminobenzene-1,4-Dicarboxylate
• 2-Aminoterephthalic Acid Dimethyl Ester
• Amino Tere Phthalate dimethyl ESter
• Aminoterephthalic acid dimethyl ester
• Dimethyl 2-Aminobenzene-1,4-Dicarboxylate
• Dimethyl 2-aminobenzene-1,4-dioate
• Dimethyl 2-aminoterephthalate
• Dimethyl 3-aminoterephthalate
• Dimethyl o-aminoterephthalate
• Methyl 2-amino-4-carbomethoxybenzoate
• NSC 20561

Dimethyl Aminoterephthalate

CAS: 5372-81-6

Formula: C₁₀H₁₁NO₄

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow to Green powder to crystal

Molecular weight: 209.20

Ref: 3B-D5462

Dimethyl aminoterephthalate, 99%

CAS: 5372-81-6

Dimethyl aminoterephthalate is used in the preparation of imidazotetrazinones as probes for the action of temozolomide. It is also used to prepare aminoquinazolines with neurokinin-2 receptor antagonist activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar pr

Formula: C₁₀H₁₁NO₄

Purity: 99%

Color and Shape: Cream to yellow to green to brown, Powder

Molecular weight: 209.20

Ref: 02-A10567

1,4-Benzenedicarboxylic acid, 2-amino-, dimethyl ester

CAS: 5372-81-6

Formula: C₁₀H₁₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 209.1986

Ref: IN-DA00I9L4

Dimethyl 2-aminoterephthalate

CAS: 5372-81-6

Dimethyl 2-aminoterephthalate

Purity: ≥95%

Color and Shape: Yellow Powder

Molecular weight: 209.20g/mol

Ref: 54-OR28713

Dimethyl aminoterephthalate

CAS: 5372-81-6

Formula: C₁₀H₁₁NO₄

Molecular weight: 209.20

Ref: 7W-GK9663

Dimethyl Aminoterephthalate

Controlled Product

CAS: 5372-81-6

Applications Dimethyl Aminoterephthalate is used to prepare imidazotetrazinones as probes for action of temozolomide. It can be used to prepare aminoquinazolines with neurokinin-2 receptor antagonist activity.
References Clark, A., et al.: J. Med. Chem., 38, 1493 (1995); Jacobs, R., et al.: Bioorg. Med. Chem. Lett., 5, 2879 (1995)

Formula: C₁₀H₁₁NO₄

Color and Shape: Neat

Molecular weight: 209.2

Ref: TR-D460350

2-Aminoterephthalic acid dimethyl ester

CAS: 5372-81-6

2-Aminoterephthalic acid dimethyl ester is a proton receptor that binds to the C-terminus of the proton receptor. It has been shown to inhibit serine protease activity and chemokine production, which may lead to dysuria. The proton receptor-binding site is composed of a five-membered heteroaryl ring with a methylthio group, which interacts with the protonated amino group at the 2 position of the 2-aminoterephthalic acid. This interaction results in an electrochemical impedance spectroscopy signal that has a low energy.

Formula: C₁₀H₁₁NO₄

Purity: Min. 98.5 Area-%

Color and Shape: Off-White Powder

Molecular weight: 209.2 g/mol

Ref: 3D-FA106354

Dimethyl 2-Aminoterephthalate

CAS: 5372-81-6

Formula: C₁₀H₁₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 209.201

Ref: 10-F066751