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CAS 53749-60-3

:

substance P fragment 4-11 acetate

Description:
Substance P fragment 4-11 acetate, with the CAS number 53749-60-3, is a peptide derived from substance P, which is a neuropeptide involved in pain perception and inflammatory processes. This specific fragment consists of a sequence of amino acids that are crucial for its biological activity. Characteristically, it exhibits properties typical of peptides, such as solubility in water and stability under physiological conditions. The acetate form indicates that it has been modified with an acetate group, which can influence its solubility and bioavailability. This fragment is often studied for its role in neurobiology and potential therapeutic applications, particularly in pain management and neuroinflammatory conditions. Its mechanism of action typically involves interaction with neurokinin receptors, particularly the NK1 receptor, which mediates various physiological responses. Overall, substance P fragment 4-11 acetate serves as an important tool in research related to neuropeptide signaling and its implications in health and disease.
Formula:C46H67N11O10S
InChI:InChI=1/C46H67N11O10S/c1-27(2)23-34(45(66)53-30(40(49)61)20-22-68-3)52-39(60)26-51-41(62)35(24-28-11-6-4-7-12-28)56-46(67)36(25-29-13-8-5-9-14-29)57-44(65)33(17-19-38(48)59)55-43(64)32(16-18-37(47)58)54-42(63)31-15-10-21-50-31/h4-9,11-14,27,30-36,50H,10,15-26H2,1-3H3,(H2,47,58)(H2,48,59)(H2,49,61)(H,51,62)(H,52,60)(H,53,66)(H,54,63)(H,55,64)(H,56,67)(H,57,65)/t30-,31?,32-,33-,34?,35-,36-/m0/s1
SMILES:CC(C)CC(C(=N[C@@H](CCSC)C(=N)O)O)N=C(CN=C([C@H](Cc1ccccc1)N=C([C@H](Cc1ccccc1)N=C([C@H](CCC(=N)O)N=C([C@H](CCC(=N)O)N=C(C1CCCN1)O)O)O)O)O)O
Synonyms:
  • Substance P (4-11)
  • H-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
  • prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycylleucyl-L-methioninamide
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Found 2 products.
  • Substance P (4-11)
    Targetmol
    + Info

    Substance P (4-11)

    CAS:
    <p>Substance P (4-11), a C-terminal fragment of Substance P, acts as a highly selective agonist for NK1 receptors, demonstrating specificity in its interaction.</p>
    Formula:C46H67N11O10S
    Color and Shape:Solid
    Molecular weight:966.16

    Ref: TM-T76455

  • Substance P (4-11)
    Biosynth
    + Info

    Substance P (4-11)

    CAS:
    <p>Substance P (4-11) H-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 is a fluorescent peptide that binds to calcium and chloride ions. It has been shown to have an affinity for both peptide and calmodulin binding. This peptide has also been shown to be highly heat stable and can be used in a wide range of temperatures. The substance P (4-11) sequence is found in porcine, rat, bovine, and human proteins. The amino acid sequence is composed of 4 amino acids: proline, glutamine, phenylalanine, and leucine. This peptide's optimum pH is 7.5 with a temperature range of 35°C to 45°C. It has been shown that the activity of this peptide decreases as the concentration increases. It has also been shown to be susceptible to aminopeptidases at high concentrations or when</p>
    Formula:C46H67N11O10S
    Purity:Min. 95%
    Molecular weight:966.16 g/mol

    Ref: 3D-FS109334

    10mg
    863.00€
    25mg
    1,019.00€
    50mg
    1,672.00€