Substance P fragment 2-11 acetate, identified by its CAS number 53749-61-4, is a peptide derived from substance P, a neuropeptide involved in pain perception and inflammatory processes. This specific fragment consists of a sequence of amino acids that retains some of the biological activity of the full substance P molecule. Characteristically, it is a small peptide, typically exhibiting properties such as solubility in water and stability under physiological conditions. The acetate form indicates that it is acetylated, which can enhance its stability and bioavailability. This fragment is often used in research to study neurogenic inflammation, pain pathways, and receptor interactions, particularly with the neurokinin-1 receptor. Its biological activity may include modulation of neurotransmitter release and involvement in various physiological responses. As with many peptides, it may also exhibit specific binding affinities and may be subject to degradation by proteolytic enzymes in biological systems. Overall, substance P fragment 2-11 acetate serves as a valuable tool in neurobiological research.

substance P fragment 2-11 acetate

53749-61-4: Substance P fragment 2-11 acetate, identified by its CAS number 53749-61-4, is a peptide derived from substance P, a neuropeptide involved in pain perception and inflammatory processes. This specific fragment consists of a sequence of amino acids that retains some of the biological activity of the full substance P molecule. Characteristically, it is a small peptide, typically exhibiting properties such as solubility in water and stability under physiological conditions. The acetate form indicates that it is acetylated, which can enhance its stability and bioavailability. This fragment is often used in research to study neurogenic inflammation, pain pathways, and receptor interactions, particularly with the neurokinin-1 receptor. Its biological activity may include modulation of neurotransmitter release and involvement in various physiological responses. As with many peptides, it may also exhibit specific binding affinities and may be subject to degradation by proteolytic enzymes in biological systems. Overall, substance P fragment 2-11 acetate serves as a valuable tool in neurobiological research.

<p>Substance P (2-11) H-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 is a peptide that is the product of proteolytic cleavage of substance P. It binds to the neurokinin receptor and induces degranulation in mast cells and sensory neurons. It has been used as a diagnostic tool for mast cell degranulation. Substance P (2-11) H-Pro-Lys-Pro-Gln-Gln-Phe has also been used to assess lung function in anesthetized animals, circulations in muscle, and changes in perfusion during surgical procedures.</p>

CAS 53749-61-4

substance P fragment 2-11 acetate

Substance P (2-11)

Ref: 3D-FS109359