CAS 537705-08-1

2-Methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide

Description:

2-Methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide, with the CAS number 537705-08-1, is a synthetic organic compound characterized by its complex structure, which includes multiple functional groups such as methoxy, acetamide, and quinazoline moieties. This compound is typically studied for its potential biological activities, particularly in the field of medicinal chemistry, where it may exhibit properties relevant to cancer treatment or other therapeutic areas. The presence of a pyridine ring suggests potential interactions with biological targets, while the quinazoline structure is often associated with kinase inhibition. Its solubility, stability, and reactivity can vary based on the specific conditions and solvents used. As with many synthetic compounds, safety and handling precautions are essential, and its pharmacological profile would require thorough investigation through in vitro and in vivo studies to determine efficacy and toxicity.

Formula: C₂₇H₂₇N₅O₃

InChI: InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)

InChI key: InChIKey=LLVZBTWPGQVVLW-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=CC(C=CCNC(COC)=O)=C2)N=CN1)C3=CC(C)=C(OC=4C=CC(C)=NC4)C=C3

Synonyms:

• Acetamide, 2-methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]-
• 2-Methoxy-N-[3-[4-[[3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl]amino]quinazolin-6-yl]allyl]acetamide
• Acetamide, 2-methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propenyl]-
• 2-Methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide

Acetamide,2-methoxy-N-[3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propenyl]-

CAS: 537705-08-1

Formula: C₂₇H₂₇N₅O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 469.5350

Ref: IN-DA00DGY9

(E/Z)-CP-724714

CAS: 537705-08-1

(E/Z)-CP-724714, comprising racemic mixtures of (E)-CP-724714 and (Z)-CP-724714 isomers, is a potent, selective, and orally active inhibitor of ErbB2 (HER2)[1].

Formula: C₂₇H₂₇N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 469.54

Ref: TM-T6046

CP-724714

CAS: 537705-08-1

CP-724714 is a small molecule that is able to inhibit the growth of cancer cells. It has been shown to be effective against HER2+ breast cancer, colorectal carcinoma cell lines, and lung carcinoma cell lines. CP-724714 causes cell cycle arrest by inhibiting the production of proteins required for DNA replication and repair. Cell proliferation inhibition can also be achieved by blocking epidermal growth factor receptors or other growth factors such as platelet-derived growth factor (PDGF). The mechanism of action may involve interference with the activation of protein kinase B (PKB), which is involved in cell signaling pathways. CP-724714 has been studied in both cell culture and clinical studies for its biological function as a cancer therapeutic agent.

Formula: C₂₇H₂₇N₅O₃

Purity: Min. 95%

Molecular weight: 469.53 g/mol

Ref: 3D-MWA70508