CAS 53772-82-0

cis-Flupenthixol

Description:

Cis-Flupenthixol is an antipsychotic medication belonging to the thioxanthene class, primarily used in the treatment of schizophrenia and other psychotic disorders. It functions as a dopamine receptor antagonist, particularly targeting D2 receptors, which helps in alleviating symptoms of psychosis. The compound exhibits a high affinity for various neurotransmitter receptors, including serotonin receptors, contributing to its therapeutic effects. Cis-Flupenthixol is characterized by its relatively long half-life, allowing for once-daily dosing in many cases. It is typically administered in the form of oral tablets or injectable formulations. Common side effects may include sedation, extrapyramidal symptoms, and weight gain, which are associated with many antipsychotic medications. The substance is also noted for its potential to cause metabolic changes and cardiovascular effects, necessitating careful monitoring during treatment. Overall, cis-Flupenthixol is an important medication in psychiatric care, providing significant benefits for individuals with severe mental health conditions while requiring attention to its side effect profile.

Formula: C₂₃H₂₅F₃N₂OS

InChI: InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5-

InChI key: InChIKey=NJMYODHXAKYRHW-DVZOWYKESA-N

SMILES: C(\CCN1CCN(CCO)CC1)=C/2\C=3C(SC=4C2=CC=CC4)=CC=C(C(F)(F)F)C3

Synonyms:

• (Z)-4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol
• 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, (Z)-
• 1-Piperazineethanol, 4-[(3Z)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-
• 4-[(3Z)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol
• 9H-Thioxanthene, 1-piperazineethanol deriv.
• Penthixol
• Z-Flupentixol
• Zuflupentixol
• alpha-Flupenthixol
• cis-(Z)-Flupenthixol
• cis-(Z)-Flupentixol
• cis-Flupenthixol
• cis-Flupentixol

Cis-flupentixol

CAS: 53772-82-0

Cis-flupentixol

Formula: C₃₃H₄₅F₃N₂O₃S

Color and Shape: Off-White

Molecular weight: 606.7822

Ref: 47-738

cis-(Z)-Flupentixol dihydrochloride

Controlled Product

CAS: 53772-82-0

cis-(Z)-Flupentixol dihydrochloride is an antipsychotic medication, which is a derivative of thioxanthene. Synthesized in laboratories, its structure is characterized by the presence of a cis-(Z) configuration, which influences its binding properties to dopamine receptors. The primary mode of action of cis-(Z)-Flupentixol dihydrochloride involves antagonism at dopamine D1 and D2 receptors, thereby modulating neurotransmitter activity in the brain. This action is critical in the attenuation of symptoms associated with psychotic disorders, through the rebalancing of dopaminergic pathways.

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 507.44 g/mol

Ref: 3D-FF23499